Results 221 to 230 of about 690,595 (340)

Loss of STARD7 Triggers Metabolic Reprogramming and Cell Cycle Arrest in Breast Cancer

Advanced Science, EarlyView.
Breast cancer cells undergo metabolic and transcriptomic reprogramming to support aberrant cell proliferation. Their mitochondria rely on the transfer of phosphatidylcholine from the endoplasmic reticulum to their membranes by STARD7, a candidate upregulated in breast cancer, to be functional.
Ewelina Dondajewska, Paula Allepuz‐Fuster, Chloé Maurizy, Alexandre Hego, Sandra Ormenese, Quentin Lion, Arnaud Blomme, Pierre Close, Arnaud Lavergne, Latifa Karim, Marc Thiry, Ivan Nemazanyy, Roopesh Krishnankutty, Jair Marques Jr, Alex von Kriegsheim, Nathaniel F. Henneman, Ganna Panasyuk, Kateryna Shostak, Alain Chariot   +18 more
wiley   +1 more source

Morphology-dependent entry kinetics and spread of influenza A virus. [PDF]

EMBO J
Peterl S, Lahr CM, Schneider CN, Meyer J, Podlipensky X, Lechner V, Villiou M, Eis L, Klein S, Funaya C, Cavalcanti-Adam EA, Graw F, Selhuber-Unkel C, Rohr K, Chlanda P.   +14 more
europepmc   +1 more source

IMMUNOLOGICAL STUDIES WITH THE VIRUS OF INFLUENZA [PDF]

, 1935
Thomas Francis, T. P. Magill
openalex   +1 more source

Lipid Droplet‐Organized MDM2‐Mediated P53 Degradation: A Metabolic Switch Governing Diet‐Driven Tumor Progression

Advanced Science, EarlyView.
Tumor‐associated TP53 inactivation correlates with lipid droplet (LD) accumulation. High‐fat diets drive Cyb5r3‐Myh9‐mediated p53 enrichment on LD surfaces, accelerating its degradation while upregulating LD‐promoting factor CD36 expression to establish a feed‐forward loop. LD suppression or dietary intervention restores p53 and inhibits tumorigenesis,
Haiyang Liu, Lin Jing, Yixin Li, Jinxing Zhou, Xiaohui Cui, Sen Li, Shijie Yang, Fangming Kan, Junfeng Du, Wentao Zhong, Sheng Yu, Ning Wang, Xing Jia, Junhui Li, Pan Nie, Zhenzhong Chen, Ying Han, Lingxi Jiang, Xiyun Yan, Hongxia Duan, Baiyong Shen   +20 more
wiley   +1 more source

The impact of highly pathogenic avian influenza H5N1 virus infection on dairy cows. [PDF]

Nat Commun
Peña-Mosca F, Frye EA, MacLachlan MJ, Rebelo AR, de Oliveira PSB, Nooruzzaman M, Koscielny MP, Zurakowski M, Lieberman ZR, Leone WM, Elvinger F, Nydam DV, Diel DG.   +12 more
europepmc   +1 more source

ANTIBODY RESPONSE OF HUMAN BEINGS FOLLOWING VACCINATION WITH INFLUENZA VIRUSES [PDF]

, 1942
George K. Hirst, E. R. Rickard, Loring Whitman, Frank L. Horsfall   +3 more
openalex   +1 more source

PIM1 Attenuates Innate Immunity to Foster Coronavirus Replication through Ubiquitin Ligase β‐TrCP‐Mediated IFNAR1 Degradation

Advanced Science, EarlyView.
Hijacking Host Kinase PIM1: A β‐Coronavirus (OC43) strategy to degrade IFNAR1 and evade antiviral immunity. Human β‐coronaviruses (OC43) exploit the proto‐oncoprotein PIM1 kinase to sabotage innate immunity. Viral RNA/proteins upregulate PIM1, which phosphorylates E3 ligase β‐TrCP1.
Qianya Wan, Lin Zhu, Cien Chen, Li Zhong, Houying Leung, Wei Li, Chang Xu, Xi Yao, Huan Hu, Mandi Wu, Yuxin Hou, Hin Chu, Yiran Wang, Sheng Chen, Mingyu Pan, Zongwei Cai, Ming‐liang He   +16 more
wiley   +1 more source

IFIT3 RNA-binding activity promotes influenza A virus infection and translation efficiency. [PDF]

J Virol
Sullivan OM, Nesbitt DJ, Schaack GA, Feltman EM, Nipper T, Kongsomros S, Reed SG, Nelson SL, King CR, Shishkova E, Coon JJ, Mehle A.   +11 more
europepmc   +2 more sources

Novel Minimal Absent Words Detected in Influenza A Virus. [PDF]

Viruses
Bigiş EZ, Yıldız E, Tagka A, Pavlopoulou A, Chrousos GP, Geronikolou S.   +5 more
europepmc   +1 more source

NEUTRALIZATION TESTS WITH SERA OF CONVALESCENT OR IMMUNIZED ANIMALS AND THE VIRUSES OF SWINE AND HUMAN INFLUENZA [PDF]

, 1936
Thomas Francis, Richard E. Shope
openalex   +1 more source