Results 231 to 240 of about 928,120 (339)

ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid‐β Pathology

Advanced Science, EarlyView.
This study identifies that ALKBH3‐driven m1A demethylation orchestrates Alzheimer's disease progression by disrupting mitochondrial and synaptic homeostasis. This epitranscriptomic mechanism suppresses PINK1‐mediated mitophagy via m1A erasure, leading to mitochondrial dysfunction, oxidative stress, elevated Aβ production, and impaired microglial ...
Yueyang Li, Sifei Yu, Kaidong Lu, Yujie Zhang, Mingjie Dong, Yan Peng, Liang Xue, Waleed Alam, Yuxuan Shui, Yi Zhou, Wuyunhan Ma, Meng Bao, Peiming Li, Peiyi Luo, Tiezhan Lu, Jiajia Li, Kang Zhang, Yuying Wang, Shuchen Yang, Nuoya Yin, Francesco Faiola, Zilong Gao, Jingfeng Zhou, Fei Zhao, Yali He, Magdalena J. Koziol   +25 more
wiley   +1 more source

Cnidium monnieri Polysaccharides Exhibit Inhibitory Effect on Airborne Transmission of Influenza A Virus. [PDF]

Viruses
Wang H, Jin Y, Li Y, Wang Y, Zhao Y, Cheng S, Li Z, Yan M, Yang Z, Chen X, Zhang Y, Yang Z, Wang Z, Liu K, Chen L.   +14 more
europepmc   +1 more source

Influenza A (H1N1) Virus [PDF]

, 2020
openaire   +1 more source

Reinforcing Calcium Overload via Inflammation‐Mediated Targeting to Amplify Pyroptosis and Antitumor Immunity

Advanced Science, EarlyView.
A neutrophil‐membrane‐camouflaged nanoplatform (RC@NMVs) exploits tumor inflammation to target and accumulate in tumors. Intracellular Ca2+ overload is triggered via lysosomal CaP dissolution and Ru red‐mediated Ca2+ channel blockade, synergistically inducing gasdermin‐mediated pyroptosis.
Yingying Liu, Yang Liu, Qin Fan, Jinqiao Zhang, Kexin Wen, Boyu Yuan, Xianzhou Cai, Ziliang Dong, Lianhui Wang   +8 more
wiley   +1 more source

Pathogenesis and Transmission of a Reassorted H1 Influenza A Virus Detected in North American Swine. [PDF]

Influenza Other Respir Viruses
Goulart DB, Souza CK, Zanella GC, Snyder CA, Zanella JC, Markin A, Arruda B, Anderson TK, Baker AL.   +8 more
europepmc   +1 more source

Influenza A Virus Protein PA-X Contributes to Viral Growth and Suppression of the Host Antiviral and Immune Responses

Journal of Virology, 2015
Tsuyoshi Hayashi, L. A. MacDonald, T. Takimoto   +2 more
semanticscholar   +1 more source

Mass‐Produced and High‐Performance Nanowell Biosensor Fabricated via Semiconductor Manufacturing for Rapid and Accurate COVID‐19 Diagnosis in the Clinical Field

Advanced Science, EarlyView.
A semiconductor‐fabricated nanowell biosensor enables rapid, scalable, and highly reproducible detection of SARS‐CoV‐2 antigens from nasal swabs within ∼10 minutes. Clinical validation in 249 retrospective and 243 prospective patient samples demonstrates high sensitivity and specificity, minimal cross‐reactivity, and robust batch‐to‐batch ...
Yoo Min Park, Zahra Rezaei, Nam Ho Bae, Donggee Rho, Da‐Seul Kim, EunYoung Go, YoungTae Seo, Seok Jae Lee, Won Chan Seo, Luke P. Lee, HeaYeon Lee, Su Ryon Shin   +11 more
wiley   +1 more source

A single mutation in nonstructural protein 1 is critical for the adaptive evolution of influenza B virus. [PDF]

Nat Commun
Jiao P, Jia X, Bai X, Zhao Y, Lin R, Fan Z, Fan W, Zhang H, Li H, Bi Y, Wang D, Liu W, Sun L.   +12 more
europepmc   +1 more source

Influenza A virus neuraminidase [PDF]

Science-Business eXchange, 2010
openaire   +1 more source

Structural Analysis of the Roles of Influenza A Virus Membrane-Associated Proteins in Assembly and Morphology

Journal of Virology, 2015
P. Chlanda, Oliver Schraidt, Susann Kummer, J. Riches, H. Oberwinkler, S. Prinz, H. Kräusslich, J. Briggs   +7 more
semanticscholar   +1 more source