Results 221 to 230 of about 928,120 (339)

Development of an influenza D virus with an eight- or nine-segment genome. [PDF]

Sci Rep
Ishida H, Murakami H, Mizuno S, Katayama M, Sekine W, Ohira K, Takenaka-Uema A, Murakami S, Nagai M, Horimoto T.   +9 more
europepmc   +1 more source

Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy

Advanced Science, EarlyView.
Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee, Chul‐Gyun Lim, Pothiappan Vairaprakash, Jong‐Min Kim, Jiyoon Kim, Ji‐Young Park, Klaus M. Hahn, Hyunbo Shim, Hae Woong Choi, Tobias S. Ulmer, Soon Jun Hong, Chungho Kim   +11 more
wiley   +1 more source

Pre-Exposure Intranasal Treatment with Neomycin Sulfate Reduces Transmission of Influenza B Virus. [PDF]

Antibiotics (Basel)
Sergeeva MV, Shamakova D, Kudrya K, Zagriadskii N, Karachevtseva DM, Matichin AA, Muzhikyan A, Stukova M.   +7 more
europepmc   +1 more source

A distinct lineage of influenza A virus from bats

Proceedings of the National Academy of Sciences of the United States of America, 2012
S. Tong, Yan Li, P. Rivailler, C. Conrardy, Danilo A. Alvarez Castillo, Li-mei Chen, S. Recuenco, J. Ellison, C. Davis, I. York, A. Turmelle, D. Moran, Shannon L. Rogers, M. Shi, Ying Tao, M. Weil, Kevin Tang, Lori Rowe, Scott A. Sammons, Xiyan Xu, M. Frace, K. Lindblade, N. Cox, L. Anderson, C. Rupprecht, R. Donis   +25 more
semanticscholar   +1 more source

Fully Humanized Bispecific T Cell Engager Shows Potent Activity in Central Nervous System and Peripheral Tumors

Advanced Science, EarlyView.
This study reports the development of a fully humanized bispecific T cell engager targeting IL13RA2, a tumor‐associated antigen enriched in glioblastoma. This off‐the‐shelf immunotherapy drives potent, antigen‐dependent T cell activation and tumor killing, and prolongs survival in experimental GBM and other solid tumors models without detectable off ...
Joseph T. Duffy, Angela Martin‐Regalado, Benedikt E. Haupt, Jacob R. Pogue, Aditi Thakur, Manuel Fierro Cota, Markella Zannikou, Sol Misener, Vera P. Krymskaya, Kathleen McCortney, Jason Miska, Craig Horbinski, Dmitri Simberg, Maciej S. Lesniak, Charles D. James, Roger Stupp, Irina V. Balyasnikova   +16 more
wiley   +1 more source

First Detection and Genetic Characterization of Influenza D Virus in Cattle in Spain. [PDF]

Vet Sci
Benito AA, Monteagudo LV, Lázaro-Gaspar S, Garza-Moreno L, Antón-Baltanás N, Quílez J.   +5 more
europepmc   +1 more source

Studying Macromolecular Composition in Cell–Cell Interfaces Using 3D Membrane Reconstitution Systems

Advanced Science, EarlyView.
A comprehensive understanding of the interactions between proteins, lipids and glycocalyx components at the immune synapse is still lacking. Here, an artificial and a semi‐artificial model contact system were established to reconstitute the cell‐cell contact in 3D. The model systems enable the examination of macromolecule enrichment or depletion at the
Franziska Ragaller, Amelie Maribel Schneider, Ellen Sjule, Renhua Sun, Xiao Han, Luca Andronico, Edward Jenkins, Michael Dustin, Adnane Achour, Erdinc Sezgin   +9 more
wiley   +1 more source

Influ-BERT: a domain-adaptive genomic language model for advancing influenza A virus research. [PDF]

Brief Bioinform
Ye R, Li L, Ribeiro de Vasconcelos AT, Song S.   +3 more
europepmc   +1 more source

Metabolic Imbalance Triggers Adaptive Remodeling to Accelerate Diploidization in Murine Haploid Embryonic Stem Cells

Advanced Science, EarlyView.
In this article, Shuai and colleagues demonstrate that metabolic remodeling drives self‐diploidization in murine haploid ESCs (haESCs). Mitochondrial dysfunction and imbalanced pyruvate metabolism underlie this process. Genome‐wide screening using haESCs identifies key mitochondrial quality‐control related genes, enabling a metabolism‐based medium that
Yi Fu, Wenhao Zhang, Yifan Zhang, Yu He, Yi Du, Yiding Zhao, Chunmeng Yao, Shengyi Sun, Xiaoyan Sheng, Qian Gao, Chao Tong, Ling Shuai   +11 more
wiley   +1 more source

Influenza C Virus in Children With Acute Bronchiolitis and Febrile Seizures. [PDF]

Pediatr Infect Dis J
Jevšnik Virant M, Petrovec M, Strle F, Mrvič T, Pokorn M, Grosek Š, Uršič T.   +6 more
europepmc   +1 more source