Results 241 to 250 of about 928,120 (339)

Gasdermin D‐Mediated Release of IL‐33 Results in Fetal Brain Developmental Abnormalities During Maternal Colitis

Advanced Science, EarlyView.
Under colitis, Gsdmd mediates the release of IL‐33 from the epithelium of pregnant mice. IL‐33 can cross the placenta and enhance the proliferative capacity of neural stem cells, ultimately resulting in behavioral deficits in the offspring. Excessive pyroptosis in the colonic epithelium also triggers the translocation of LPS, which in turn increases ...
Huiyang Jia, Shukui Zhang, Kai Ma, Jie Zhou, Jianwei Jiao   +4 more
wiley   +1 more source

Disruption of influenza A virus transmission in gene-edited pigs. [PDF]

Emerg Microbes Infect
Kwon T, Morozov I, McDowell CD, Lyoo EL, Artiaga BL, Li Y, Assato P, White SN, Beaton BP, Delhon G, Gaudreault NN, Richt JA.   +11 more
europepmc   +1 more source

Copper Depletion Nanoparticles Potentiate Cancer Immunotherapy by Avoiding Innate and Adaptive Immune Resistance

Advanced Science, EarlyView.
A mitochondria‐targeted copper depletion nanoplatform (CYN‐CDA@Alb) was developed to selectively disrupt tumor mitochondria copper, which then reprogrammed the tumor immune microenvironment by depressing PD‐L1 and CD47 expression simultaneously. By doing this, CYN‐CDA@Alb reversed radiotherapy‐induced immune tolerance, showing the potential usage of ...
Zaigang Zhou, Ke Li, Xuelan Li, Lei Yi, Zhengxiang Wang, Huan Ding, Sheng Wu, Feiyu Liu, Yuan Li, Rui Cheng, Jianliang Shen   +10 more
wiley   +1 more source

Immunity to hemagglutinin and neuraminidase results in additive reductions in airborne transmission of influenza H1N1 virus in ferrets. [PDF]

Sci Adv
Septer KM, Sim DG, Patel DR, Field CJ, Wang W, Roder AE, Chung M, Restori KH, Norton EB, Exten C, Ghedin E, Sutton TC.   +11 more
europepmc   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

Structural and functional characterization of the antigenicity of influenza A virus hemagglutinin subtype H15. [PDF]

Cell Rep
Bhavsar D, León AN, Hsu WL, Puente-Massaguer E, Ferguson JA, Han J, Wilson P, Ward AB, Krammer F.   +8 more
europepmc   +1 more source

Influenza A (H5N1) Virus [PDF]

, 2020
openaire   +1 more source

Structural Insights Into Man9 Recognition by the HIV Antibody 2G12 Revealed by Paramagnetic NMR

Advanced Science, EarlyView.
The HIV gp120 glycoprotein displays Man9 oligomannose structures that are recognized by the neutralizing antibody 2G12. Detailed characterization of the binding epitope in solution is important for immunogen design but remains challenging, since the signals of the terminal mannoses from the three arms of Man9 (D1, D2, and D3) cannot be distinguished in
Adrián Silva‐Díaz, Paola Oquist‐Phillips, Noelia de la Cruz, Inés Lera‐Lasso, Laura Castañar, Javier Rojo, Javier Ramos‐Soriano, Ángeles Canales   +7 more
wiley   +1 more source

<i>Rhus coriaria Linn</i> Extract as a Natural Inhibitor of Influenza A Virus Replication In Vitro. [PDF]

Curr Issues Mol Biol
Prezioso C, Savo Sardaro ML, Frezza F, Limongi D, Velotto S, Lupacchini L, D'Auria G, De Angelis M, Nencioni L, Checconi P.   +9 more
europepmc   +1 more source

Influenza A virus neuraminidase [PDF]

Science-Business eXchange, 2009
openaire   +1 more source