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Direct RNA Sequencing of the Coding Complete Influenza A Virus Genome
Scientific Reports, 2018 For the first time, a coding complete genome of an RNA virus has been sequenced in its original form. Previously, RNA was sequenced by the chemical degradation of radiolabeled RNA, a difficult method that produced only short sequences.
Matthew W. Keller +9 more
semanticscholar +1 more source
Influenza A virus uncoating [PDF]
, 2020 Influenza A virus (IAV) is an enveloped virus of the Orthomyxoviridae with a negative-sense single-stranded RNA genome. During virus cell entry, viral and cellular cues are delivered in a stepwise manner within two distinct cellular compartments-the endosomes and the cytosol.
openaire +4 more sources
Influenza A virus ribonucleoproteins form liquid organelles at endoplasmic reticulum exit sites
Nature Communications, 2018 Influenza A virus has an eight-partite RNA genome that during viral assembly forms a complex containing one copy of each RNA. Genome assembly is a selective process driven by RNA-RNA interactions and is hypothesized to lead to discrete punctate ...
Marta Alenquer +5 more
semanticscholar +1 more source
Human-Origin Influenza A(H3N2) Reassortant Viruses in Swine, Southeast Mexico
Emerging Infectious Diseases, 2019 The genetic diversity of influenza A viruses circulating in swine in Mexico complicates control efforts in animals and presents a threat to humans, as shown by influenza A(H1N1)pdm09 virus. To describe evolution of swine influenza A viruses in Mexico and
Martha I. Nelson +9 more
doaj +1 more source
Influenza pathogenesis: mechanisms of modulation by agent proteins
Журнал инфектологии, 2015 Modern concepts of the influence of the proteins from viruses-etiological agents of flu – Influenzavirus A, B and C (Orthomyxoviridae) – on the development of different elements of the main disease pathogenesis are analyzed in the review.
M. Yu. Shchelkanov +7 more
doaj +1 more source
Инфекция и иммунитет, 2021 Influenza and other acute respiratory viral infections are the most common infectious diseases of our time, causing a significant harm to human health as well as great economic damage.
N. G. Klivleyeva +9 more
doaj +1 more source
Evolution of Influenza A Virus by Mutation and Re-Assortment
International Journal of Molecular Sciences, 2017 Influenza A virus (IAV), a highly infectious respiratory pathogen, has continued to be a significant threat to global public health. To complete their life cycle, influenza viruses have evolved multiple strategies to interact with a host.
Wenhan Shao +4 more
semanticscholar +1 more source
Development of DNA-Biochip for Identification of Influenza A Virus Subtypes
Проблемы особо опасных инфекций, 2012 Developed was the DNA-biochip to identify subtypes of influenza A virus, pathogenic for humans. Microchip was capable of detecting H1, H3, H5-subtypes of hemagglutinin (including H1-subtype of pandemic A/H1N1(2009) influenza virus ) and neuraminidase ...
A. N. Shikov +8 more
doaj +1 more source
Influenza A virus M2 protein triggers mitochondrial DNA-mediated antiviral immune responses
Nature Communications, 2019 Cytosolic mitochondrial DNA (mtDNA) activates cGAS-mediated antiviral immune responses, but the mechanism by which RNA viruses stimulate mtDNA release remains unknown.
Miyu Moriyama, T. Koshiba, T. Ichinohe
semanticscholar +1 more source
STUDIES ON THE VIRUS OF INFLUENZA [PDF]
Journal of Experimental Medicine, 1936 1. Evidence is presented indicating the presence of a filtrable virus in the nasopharyngeal secretions of individuals suffering from influenza. 2. An attempt to transfer influenza from one human being to another by means of filtered nasopharyngeal washings resulted in the production in the inoculated volunteer of a common cold.
Katherine C. Mills +2 more
openaire +3 more sources