Results 61 to 70 of about 688,416 (341)

Impact of Protein Nitration on Influenza Virus Infectivity and Immunogenicity

open access: yesMicrobiology Spectrum, 2022
Influenza viruses are deadly respiratory pathogens of special importance due to their long history of global pandemics. During influenza virus infections, the host responds by producing interferons, which activate interferon-stimulated genes (ISGs ...
Harrison Dulin   +6 more
doaj   +1 more source

Reassessing the role of the NLRP3 inflammasome during pathogenic influenza A virus infection via temporal inhibition

open access: yesScientific Reports, 2016
The inflammasome NLRP3 is activated by pathogen associated molecular patterns (PAMPs) during infection, including RNA and proteins from influenza A virus (IAV).
M. Tate   +9 more
semanticscholar   +1 more source

The clinical characteristics of pneumonia patients coinfected with 2019 novel coronavirus and influenza virus in Wuhan, China

open access: yesJournal of Medical Virology, 2020
The outbreak of 2019 novel coronavirus (COVID‐19) infection emerged in Wuhan, China, in December 2019. Since then the novel coronavirus pneumonia disease has been spreading quickly and many countries and territories have been affected, with major ...
Q. Ding   +4 more
semanticscholar   +1 more source

Influenza virus infections [PDF]

open access: yesPostgraduate Medical Journal, 1973
Summary Ninety-six strains of influenza A and 113 influenza B were found in the two MRC/PHLS surveys. In the general practitioner survey the majority of strains were isolated from cases diagnosed as influenza but in hospital most came from cases diagnosed as having other respiratory infections.
openaire   +3 more sources

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Epitope specificity plays a critical role in regulating antibody-dependent cell-mediated cytotoxicity against influenza A virus

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2016
Significance In addition to neutralizing antigens, antibodies are also capable of stimulating cellular responses through Fc–Fc receptor interactions.
Wenqian He   +10 more
semanticscholar   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

Etiological analysis of influenza-like cases in Taizhou City, Zhejiang Province from 2013 to 2022

open access: yesShanghai yufang yixue
ObjectiveTo analyze the etiological results of influenza-like case surveillance in Taizhou, Zhejiang Province from 2013 to 2022, to timely understand the epidemic trend of influenza viruses and the change rule of dominant virus strains, and to provide ...
WANG Ziyi   +3 more
doaj   +1 more source

Giant Magnetoresistance-based Biosensor for Detection of Influenza A Virus

open access: yesFrontiers in Microbiology, 2016
We have developed a simple and sensitive method for the detection of influenza A virus based on giant magnetoresistance (GMR) biosensor. This assay employs monoclonal antibodies to viral nucleoprotein (NP) in combination with magnetic nanoparticles (MNPs)
Venkatramana D. Krishna   +3 more
semanticscholar   +1 more source

Short peptide perturbs spermatogenesis via immune microenvironment dysregulation and mitochondrial imbalance

open access: yesFEBS Open Bio, EarlyView.
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley   +1 more source

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