Results 1 to 10 of about 18,784 (176)

Detection of Two High Pathogenicity Avian Influenza Virus (HPAIV) Subtypes, H5N1 and H5N5, in a Mass Mortality Event in Wild Seabirds and Co-Location With Dead Seals. [PDF]

Transbound Emerg Dis
H5Nx Clade 2.3.4.4b high pathogenicity avian influenza viruses (HPAIVs) have been detected repeatedly in Great Britain (GB) since autumn 2020, with H5N1 dominating detections but with low level detection of H5N5 during 2025. Globally, these viruses have caused mass mortalities in captive and wild avian and mammalian populations, including terrestrial ...
Falchieri M, Bentley E, Coombes HA, Mollett BC, Terrey J, Holland S, Stubbings E, Mcginn N, Cooper J, Ahmad S, Lewis J, Clifton B, Collinson N, Aegerter J, Venkatesh D, Russell DJF, James J, Reid SM, Banyard AC.   +18 more
europepmc   +3 more sources

Influenza A Virus H5N1 Subtype: Resurgent Interspecies and Intercontinental Transmission, and a New Host [PDF]

Pathogens
It has been more than 25 years since the avian influenza A virus (IAV) H5N1 subtype emerged in humans in 1997. Since then, this virus has become endemic in poultry and wild birds and has been causing sporadic infections in humans.
Matloob Husain
doaj   +4 more sources

Evolution of H5N1 Cross-Species Transmission: Adaptive Mutations Driving Avian-to-Human Infection. [PDF]

Adv Genet (Hoboken)
This review synthesizes current knowledge on the molecular mechanisms underpinning H5N1's host adaptation, focusing on key mutations in viral proteins. Critical mutations are discussed in detail, highlighting their roles in altering receptor specificity, promoting antiviral resistance, and expanding viral tropism. The review underscores the urgent need
Man W, Du L, Liu Y, Pang Z, Zhu H, Hong B, Xu Z, Fan H.   +7 more
europepmc   +2 more sources

A single dose of DNA vaccine based on conserved H5N1 subtype proteins provides protection against lethal H5N1 challenge in mice pre-exposed to H1N1 influenza virus [PDF]

Virology Journal, 2010
Background Highly pathogenic avian influenza virus subtype H5N1 infects humans with a high fatality rate and has pandemic potential. Vaccination is the preferred approach for prevention of H5N1 infection.
Chang Haiyan, Huang Chaoyang, Wu Jian, Fang Fang, Zhang Wenjie, Wang Fuyan, Chen Ze   +6 more
doaj   +2 more sources

Evidence of High Pathogenic Avian Influenza H5N1 Clade 2.3.4.4b Among Poultry in Ghana From 2021 to 2022. [PDF]

Vet Med Sci
Ghana experienced outbreaks of highly pathogenic avian influenza A H5N1 among poultry from 2021 to 2022. Analysing poultry, pigs, and environmental samples showed H5N1 prevalence of 2.36% (63/2640) among poultry only. The clade 2.3.4.4b virus showed mammalian adaptive motifs in haemagglutinin, emphasising the need for ongoing genomic surveillance among
Nyarko SO, Asante IA, Sarpong GM, Boatemaa L, Kwasah L, Awuku-Larbi Y, Magnusen V, Wutsika J, Ago S, Amenuvor EAA, Adusei-Poku M, Ntim NAA, Wordui J, Sekyi-Yorke AN, Takyi C, Nyarko JA, Quarcoo JA, Doku I, Tackie RA, Odoom T, Danso F, Nyarko EO, Asiedu W, Mingle DL, Attram N, Cameron-Paintsil S, Terrel S, Miranda H, Ampofo WK.   +28 more
europepmc   +2 more sources

Avian influenza overview September-November 2025. [PDF]

EFSA J
Abstract Between 6 September and 28 November 2025, 2896 highly pathogenic avian influenza (HPAI) A(H5) virus detections were reported in domestic (442) and wild (2454) birds in 29 countries in Europe. The magnitude and geographical extent of these detections were unprecedented for this time of the year, particularly in wild birds.
European Food Safety Authority, European Centre for Disease Prevention and Control, European Union Reference Laboratory for Avian Influenza, Buczkowski H, Ducatez M, Fusaro A, Gonzales JL, Kuiken T, Mirinavičiūtė G, Ståhl K, Staubach C, Svartström O, Terregino C, Willgert K, Alarcón E, Kohnle L.   +15 more
europepmc   +2 more sources

Highly pathogenic avian influenza A virus subtype H5N1 (clade 2.3.4.4b) isolated from a natural protected area in Peru. [PDF]

Microbiol Resour Announc
Landazabal-Castillo S, Suarez-Agüero D, Alva-Alvarez L, Mamani-Zapana E, Mayta-Huatuco E.   +4 more
europepmc   +2 more sources

Serological survey for avian influenza virus infection of backyard poultry and poultry workers in Baghdad and Basrah provinces, Iraq [PDF]

Bulgarian Journal of Veterinary Medicine, 2020
The aim of this study was to determine the prevalence of avian influenza virus (AIV) subtype H5N1 among backyard birds and poultry workers. The study included backyard birds (chickens and ducks) in rural areas of Baghdad and Basrah provinces, Iraq. Rural
S. Jaber, H. T. Thwiny
doaj   +1 more source

A recombinant vaccine of H5N1 HA1 fused with foldon and human IgG Fc induced complete cross-clade protection against divergent H5N1 viruses. [PDF]

PLoS ONE, 2011
Development of effective vaccines to prevent influenza, particularly highly pathogenic avian influenza (HPAI) caused by influenza A virus (IAV) subtype H5N1, is a challenging goal.
Lanying Du, Virtual Ho-Chuen Leung, Xiujuan Zhang, Jie Zhou, Min Chen, Wu He, Hai-Ying Zhang, Chris C S Chan, Vincent Kwok-Man Poon, Guangyu Zhao, Shihui Sun, Lifeng Cai, Yusen Zhou, Bo-Jian Zheng, Shibo Jiang   +14 more
doaj   +1 more source

H5Nx Viruses Emerged during the Suppression of H5N1 Virus Populations in Poultry

Microbiology Spectrum, 2021
Highly pathogenic avian influenza (HPAI) H5 viruses have posed a substantial pandemic threat through repeated human infection since their emergence in China in 1996. Nationwide control measures, including vaccination of poultry, were implemented in 2005,
Yao-Tsun Li, Yvonne C. F. Su, Gavin J. D. Smith   +2 more
doaj   +1 more source