Determinants of Antiviral Effectiveness in Influenza Virus A Subtype H5N1 [PDF]
Oseltamivir is widely used as treatment for influenza virus A subtype H5N1 (hereafter, "H5N1") infection but, like any intervention, is not always effective.We used Avian Influenza Registry data from 10 countries to examine the risk of death in 215 patients with confirmed H5N1 infection who were treated with oseltamivir, according to viral clade, age ...
Paul K.S. Chan +15 more
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Avian Influenza Virus Subtype H5N1 in Pigeons: A Conventional Serological Detection [PDF]
M. Daud AK +11 more
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Massive Mobilization of Dendritic Cells During Influenza A Virus Subtype H5N1 Infection of Nonhuman Primates [PDF]
Highly pathogenic avian influenza virus infection is characterized by a marked inflammatory response, but the impact of infection on dendritic cells (DCs) is unknown. We show that influenza A virus subtype H5N1 infection rapidly and profoundly impacts DCs in cynomolgus macaques, increasing the number of blood myeloid and plasmacytoid DCs by 16- and 60 ...
Adam C. Soloff +6 more
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Simultaneous detection of influenza virus type B and influenza A virus subtypes H1N1, H3N2, and H5N1 using multiplex real-time RT-PCR [PDF]
Use of multiplex real-time reverse transcription polymerase chain reaction (RT-PCR) for the simultaneous detection of influenza type B virus and influenza A virus subtypes H5N1, H3N2, and H1N1 has been described. The method exhibited a high specificity and sensitivity of approximately 10(1)-10(2) copies per microliter or 10(-3)-10(-2) TCID50/L for each
Fang Shisong +11 more
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Avian Influenza Virus A Subtype H5N1
Latar Belakang: Avian influenza adalah infeksi virus menular yang menyerang unggas, hewan, dan manusia di seluruh dunia. Sebagian besar infeksi pada manusia disebabkan oleh virus influenza tipe A dan B, sedangkan unggas hanya terinfeksi oleh influenza tipe A. Isi: Masa inkubasi umumnya 2 sampai 7 hari, tapi bisa selama 8 sampai 9 hari.
Erza Anugrah, M. Almutaali
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Isocyanides as Influenza A Virus Subtype H5N1 Wild‐Type M2 Channel Inhibitors
AbstractBasic bulky amines such as amantadine are well‐characterized M2 channel blockers, useful for treating influenza. Herein we report our surprising findings that charge‐neutral, bulky isocyanides exhibit activities similar to—or even higher than—that of amantadine.
Shuwen Wu +14 more
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Generation and characterisation of monoclonal antibodies against influenza virus A, subtype H5N1 [PDF]
The emergence of highly pathogenic avian influenza A virus (HPAIV) subtype H5N1 in 1997 has since resulted in large outbreaks in poultry and in transmission from poultry to humans, mostly in southeast Asia, but also in several European countries. Effective diagnosis and control measures are essential for the management of HPAIV infections. To develop a
Linke, Sonja +5 more
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Epidemiology of the Influenza A Virus H5N1 Subtype and Memory of Immunity to the H2N2 Subtype [PDF]
In their recent paper, Peter Palese and Taia T. Wang proposed a hypothesis to explain how an older circulating subtype of influenza A virus is replaced with a novel subtype (1). They and others also published experimental evidence supporting their hypothesis on the extinction of seasonal H1N1 viruses by the 2009 pandemic H1N1 viruses (2). Although they
Masanori Terajima +2 more
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H5Nx Viruses Emerged during the Suppression of H5N1 Virus Populations in Poultry
Highly pathogenic avian influenza (HPAI) H5 viruses have posed a substantial pandemic threat through repeated human infection since their emergence in China in 1996. Nationwide control measures, including vaccination of poultry, were implemented in 2005,
Yao-Tsun Li +2 more
doaj +1 more source
A study of analysis PB1-F2 protein of Influenza Viruses A/H1N1pdm09, A/ H3N2, and A/H5N1
Abstrak Tujuan. Protein PB1-F2 (polymerase basic 1-frame 2) adalah protein terbaru yang ditemukan pada virus Influenza dan telah terbukti berperan dalam induksi kematian sel dan patogenitas. Tujuan dari tulisan ini adalah untuk menganalisis protein PB1-
Hana Apsari Pawestri +1 more
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