Results 181 to 190 of about 114,208,131 (218)

Understanding of Drug-Target Interactions: A case Study in Influenza Virus A Subtype H5N1

AIP Conference Proceedings, 2007
This study aims at gaining insight into molecular mechanisms of action of three drug targets of the life cycle of influenza virus A subtype H5N1, namely Hemagglutinin (H5), Neuraminidase (N1) and M2 ion channel (M2), using molecular mechanics and molecular dynamics techniques.
Thanyada Rungrotmongkol, Maturos Malaisree, Panita Decha, Chittima Laohpongspaisan, Ornjira Aruksakunwong, Pathumwadee Intharathep, Somsak Pianwanit, Pornthep Sompornpisut, Vudhichai Parasuk, Eugene Megnassan, Vladimir Frecer, Stanislav Miertus, Supot Hannongbua, Theodore E. Simos, George Maroulis   +14 more
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Rescue of H5N1 subtypeavian influenza A viruslethal to mice

Chinese Journal of Agricultural Biotechnology, 2007
AbstractAvian influenza virus is acquiring the ability to cross the species barrier between birds and mammals. However, the genetic mechanism of this ability is not well known. We successfully rescued aninfluenza A virusA/Chicken/Guangdong/03 (H5N1), which is highly pathogenic to both SPF chickens and BALB/c mice, by plasmid-based reverse genetics. The
Pan Wei-Qi, Liu Ming, Zhang Yun, Liu Chun-Guo, Yang Tao, Li Jing-Peng   +5 more
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A Latex Agglutination Test for the Rapid Detection of Avian Influenza Virus Subtype H5N1 and its Clinical Application [PDF]

Journal of Veterinary Diagnostic Investigation, 2007
A rapid and simple latex agglutination test (LAT) for the detection of avian influenza virus (AIV) subtype H5N1 in chicken allantoic fluids, tracheal swabs, and tissues was developed. Monoclonal antibodies against the hemagglutinin glycoprotein of H5N1 were covalently coupled onto the surface of carboxylated latex bead using a water-soluble ...
Anding Zhang, Yunfeng Song, Huanchun Chen   +2 more
exaly   +3 more sources

Highly Pathogenic Avian Influenza Virus Subtype H5N1 in Mute Swans (Cygnus olor) in Central Bosnia

Avian Diseases, 2010
In order to determine the actual prevalence of avian influenza viruses (AIVs) in wild birds in Bosnia and Herzegovina, extensive surveillance was carried out between October 2005 and April 2006. A total of 394 samples representing 41 bird species were examined for the presence of influenza A virus using virus isolation in embryonated chicken eggs, PCR,
Goletić, Teufik, Gagić, Abdulah, Residbegović, Emina, Kustura, Aida, Kavazović, Aida, Savić, Vladimir, Harder, Timm, Starick, Elke, Zohari Siamak   +8 more
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Characterisation and haemagglutinin gene epitope mapping of a variant strain of H5N1 subtype avian influenza virus

Veterinary Microbiology, 2013
H5N1 avian influenza virus (AIV) undergoes rapid evolution, and its antigenicity needs to be constantly evaluated in order to update the vaccine strain. In this report, a clade 7.2 AIV isolate named A/Chicken/Huadong/4/2008 (DT) is identified. Antigenic analysis revealed that DT had a significant low cross-reactive HI titre with antiserum against a ...
Yanfang, Li, Xiaojian, Zhang, Quangang, Xu, Qiang, Fu, Yinbiao, Zhu, Sujuan, Chen, Daxin, Peng, Xiufan, Liu   +7 more
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Susceptibility and transmissibility of pigeons to Asian lineage highly pathogenic avian influenza virus subtype H5N1

Avian Pathology, 2007
To determine whether or not pigeons are susceptible to infection with Asian lineage highly pathogenic (HP) avian influenza virus (AIV) subtype H5N1 and can serve as a transmission host for H5N1 HPAIV, we experimentally infected 187 young and adult pigeons with five different isolates of H5N1 HPAIV and co-habited some experimentally infected pigeons ...
Yuehuan, Liu, Jiao, Zhou, Hanchun, Yang, Weiguang, Yao, Weidong, Bu, Bing, Yang, Weiping, Song, Yanni, Meng, Jian, Lin, Chunhua, Han, Junjie, Zhu, Zhijun, Ma, Jingyi, Zhao, Xiuqing, Wang   +13 more
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Isolation and Identification of Highly Pathogenic Avian Influenza Virus Subtype H5N1 in Peafowl (Pavo cristatus)

Avian Diseases Digest, 2010
An outbreak of highly pathogenic avian influenza (HPAI) virus subtype H5N1 was first diagnosed in a "backyard" flock of peafowl (Pavo cristatus) raised on palace premises in the Kingdom of Saudi Arabia in December 3, 2007. The flock consisted of 40 peafowl, and their ages ranged from 3 to 5 years old.
Mahmoud Moussa, Ismail, Owais Ahmed, Khan, Giovanni, Cattoli, Huaguang, Lu   +3 more
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Isolation and characterization of influenza A virus (subtype H5N1) that caused the first highly pathogenic avian influenza outbreak in chicken in Bhutan

Veterinary Microbiology, 2012
We characterized Influenza A/H5N1 virus that caused the first outbreak of highly pathogenic avian influenza (HPAI) in chickens in Bhutan in 2010. The virus was highly virulent to chicken, killing them within two days of the experimental inoculation with an intravenous pathogenicity index (IVPI) of 2.88.
S C, Dubey, N, Dahal, S, Nagarajan, C, Tosh, H V, Murugkar, K, Rinzin, B, Sharma, R, Jain, M, Katare, S, Patil, R, Khandia, Z, Syed, S, Tripathi, P, Behera, M, Kumar, D D, Kulkarni, Lal, Krishna   +16 more
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[In vitro study of antiviral activity of Myramistin against subtypes H3N2 and H5N1 of influenza virus].

Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2009
In vitro antiviral effect of myramistin on influenza virus (MDCK cell culture) was studied. The drug showed significant dose-dependent antiviral activity against the virus. When used prophylactically (1 hour before exposure to the virus) in subtoxic doses, myramistin was effective in inhibiting replication of the influenza virus [strains A/Aichi/2/68 ...
A P, Agafonov, M O, Skarnovich, V A, Petrishchenko, L N, Shishkina, A N, Sergeev, V V, Svistov, I V, Smirnov, N A, Kirichenko, Iu S, Krivoshein   +8 more
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Rapid detection of the avian influenza virus H5N1 subtype in Egypt

2016
Influenza A virus continue to cause widespread morbidity and mortality. The unprecedented spread of highly pathogenic avian influenza virus subtype H5N1 in Egypt is threatening poultry and public health systems. Effective diagnosis and control management are needed to control the disease. To this end, polyclonal antibodies (PAbs) were developed against
Shoman, SA, Khodier, MH
openaire   +1 more source