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Influenza A hemagglutinin virus-like particles confer protection against influenza B virus infection [PDF]

Emerging Microbes and Infections
Influenza A hemagglutinin (HA), neuraminidase, and/or M2e-containing virus-like particles (VLPs) induce immune responses that contribute to protection against multiple influenza A virus subtypes.
Jie Mao, Ki Back Chu, Gi-Deok Eom, Keon-Woong Yoon, Su In Heo, Hae-Ji Kang, Sung Soo Kim, Fu-Shi Quan   +7 more
doaj   +4 more sources

A potential Chinese medicine monomer against influenza A virus and influenza B virus: isoquercitrin [PDF]

Chinese Medicine, 2023
Background Influenza viruses, especially Influenza A virus and Influenza B virus, are respiratory pathogens and can cause seasonal epidemics and pandemics. Severe influenza viruses infection induces strong host-defense response and excessive inflammatory
Rongbo Luo, Chaoxiang Lv, Tiecheng Wang, Xiuwen Deng, Mingwei Sima, Jin Guo, Jing Qi, Weiyang Sun, Beilei Shen, Yuanguo Li, Donghui Yue, Yuwei Gao   +11 more
doaj   +4 more sources

Antigenic analysis of the influenza B virus hemagglutinin protein. [PDF]

Virol Sin, 2023
Influenza B viruses (IBVs) primarily infect humans and are a common cause of respiratory infections in humans. Here, to systematically analyze the antigenicity of the IBVs Hemagglutinin (HA) protein, 31 ​B/Victoria and 19 ​B/Yamagata representative circulating strains were selected from Global Initiative of Sharing All Influenza Data (GISAID), and ...
Zhang M, Yang C, Wu X, Wang Y, Wang L, Cui Q, Tong J, An Y, Cai M, Cheng S, Jiang Q, Wang Y, Zhao C, Wang Y, Huang W.   +14 more
europepmc   +3 more sources

A comprehensive review of influenza B virus, its biological and clinical aspects [PDF]

Frontiers in Microbiology
Influenza B virus (IBV) stands as a paradox, often overshadowed by its more notorious counterpart, influenza A virus (IAV). Yet, it remains a captivating and elusive subject of scientific inquiry.
Muhammad Awais Ashraf, Muhammad Awais Ashraf, Muhammad Asif Raza, Muhammad Asif Raza, Muhammad Nabeel Amjad, Muhammad Nabeel Amjad, Ghayyas ud Din, Ghayyas ud Din, Lihuan Yue, Bei Shen, Lingdie Chen, Lingdie Chen, Wei Dong, Huiting Xu, Yihong Hu, Yihong Hu   +15 more
doaj   +2 more sources

Multivalent Epigraph Hemagglutinin Vaccine Protects against Influenza B Virus in Mice [PDF]

Pathogens
Influenza B virus is a respiratory pathogen that contributes to seasonal epidemics, accounts for approximately 25% of global influenza infections, and can induce severe disease in young children.
Erika Petro-Turnquist, Brigette Corder Kampfe, Amber Gadeken, Matthew J. Pekarek, Eric A. Weaver   +4 more
doaj   +2 more sources

Early peripheral blood lymphocyte subsets and cytokines in predicting the severity of influenza B virus pneumonia in children [PDF]

Frontiers in Cellular and Infection Microbiology, 2023
BackgroundChildren with influenza B virus infection have a higher susceptibility and higher severity of illness. The activation and disorder of immune function play an important role in the severity of influenza virus infection.
Lu Ma, Jingli Yan, Wenliang Song, Bo Wu, Zeyu Wang, Wei Xu   +5 more
doaj   +2 more sources

Influenza B Virus Vaccine Innovation through Computational Design. [PDF]

Pathogens
As respiratory pathogens, influenza B viruses (IBVs) cause a significant socioeconomic burden each year. Vaccine and antiviral development for influenza viruses has historically viewed IBVs as a secondary concern to influenza A viruses (IAVs) due to their lack of animal reservoirs compared to IAVs. However, prior to the global spread of SARS-CoV-2, the
Pekarek MJ, Weaver EA.
europepmc   +4 more sources

Influenza B Virus Encephalitis [PDF]

Clinical Infectious Diseases, 1999
Acute encephalitis and postinfectious encephalopathy have been reported infrequently in association with influenza A and B virus infections. We report herein a case of a 6-year-old girl with acute influenza B virus encephalitis resulting in neurological sequelae.
J A, McCullers, S, Facchini, P J, Chesney, R G, Webster   +3 more
openaire   +2 more sources

Influenza B Virus Infection Is Enhanced Upon Heterotypic Co-infection With Influenza A Virus [PDF]

Frontiers in Microbiology, 2021
Homotypic co-infections with influenza viruses are described to increase genetic population diversity, to drive viral evolution and to allow genetic complementation. Less is known about heterotypic co-infections between influenza A (IAV) and influenza B (IBV) viruses.
Nicolas Malausse, Nicolas Malausse, Sylvie van der Werf, Nadia Naffakh, Sandie Munier   +4 more
openaire   +4 more sources

Safety, Immunogenicity, and Protective Efficacy of a Chimeric A/B Live Attenuated Influenza Vaccine in a Mouse Model

Microorganisms, 2021
Influenza A and B viruses cause significant morbidity and mortality worldwide. Current influenza vaccines are composed of three or four strains: A/H1N1, A/H3N2, and B (Victoria and Yamagata lineages).
Ekaterina Stepanova, Elena Krutikova, Pei-Fong Wong, Victoria Matyushenko, Ekaterina Bazhenova, Irina Isakova-Sivak, Larisa Rudenko   +6 more
doaj   +1 more source