Results 31 to 40 of about 247,988 (211)

No serological evidence that harbour porpoises are additional hosts of influenza B viruses. [PDF]

PLoS ONE, 2014
Influenza A and B viruses circulate among humans causing epidemics almost annually. While various hosts for influenza A viruses exist, influenza B viruses have been detected only in humans and seals.
Rogier Bodewes, Marco W G van de Bildt, Cornelis E van Elk, Paulien E Bunskoek, David A M C van de Vijver, Saskia L Smits, Albert D M E Osterhaus, Thijs Kuiken   +7 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

POPULATION IMMUNITY TO INFLUENZA VIRUS A(H1N1)pdm09, A(H3N2) AND B IN THE ADULT POPULATION OF THE RUSSIAN FEDERATION LONG-TERM RESEARCH RESULTS

Инфекция и иммунитет, 2017
Analysis of changes in the population immunity level in adults for more than 20 Russian cities, collaborating with the Federal Center for Influenza, to circulating influenza viruses A(H1N1)pdm09, A(H3N2) and B in the period from 2009 to 2015 performed ...
O. S. Konshina, A. A. Sominina, E. A. Smorodintseva, K. A. Stolyarov, I. Yu. Nikonorov   +4 more
doaj   +1 more source

Identification of a PA-binding peptide with inhibitory activity against influenza A and B virus replication. [PDF]

PLoS ONE, 2009
There is an urgent need for new drugs against influenza type A and B viruses due to incomplete protection by vaccines and the emergence of resistance to current antivirals.
Kerstin Wunderlich, Daniel Mayer, Charlene Ranadheera, Anne-Sophie Holler, Benjamin Mänz, Arnold Martin, Geoffrey Chase, Werner Tegge, Ronald Frank, Ulrich Kessler, Martin Schwemmle   +10 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Evolution of the neuraminidase gene of seasonal influenza A and B viruses in Thailand between 2010 and 2015.

PLoS ONE, 2017
The neuraminidase inhibitors (NAIs) oseltamivir and zanamivir are commonly used for the treatment and control of influenza A and B virus infection. However, the emergence of new influenza virus strains with reduced susceptibility to NAIs may appear with ...
Nipaporn Tewawong, Preeyaporn Vichiwattana, Sumeth Korkong, Sirapa Klinfueng, Nungruthai Suntronwong, Thanunrat Thongmee, Apiradee Theamboonlers, Sompong Vongpunsawad, Yong Poovorawan   +8 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

The epidemiological signature of influenza B virus and its B/Victoria and B/Yamagata lineages in the 21st century.

PLoS ONE, 2019
We describe the epidemiological characteristics, pattern of circulation, and geographical distribution of influenza B viruses and its lineages using data from the Global Influenza B Study.
Saverio Caini, Gabriela Kusznierz, Verònica Vera Garate, Sonam Wangchuk, Binay Thapa, Francisco José de Paula Júnior, Walquiria Aparecida Ferreira de Almeida, Richard Njouom, Rodrigo A Fasce, Patricia Bustos, Luzhao Feng, Zhibin Peng, Jenny Lara Araya, Alfredo Bruno, Doménica de Mora, Mónica Jeannette Barahona de Gámez, Richard Pebody, Maria Zambon, Rocio Higueros, Rudevelinda Rivera, Herman Kosasih, Maria Rita Castrucci, Antonino Bella, Hervé A Kadjo, Coulibaly Daouda, Ainash Makusheva, Olga Bessonova, Sandra S Chaves, Gideon O Emukule, Jean-Michel Heraud, Norosoa H Razanajatovo, Amal Barakat, Fatima El Falaki, Adam Meijer, Gé A Donker, Q Sue Huang, Tim Wood, Angel Balmaseda, Rakhee Palekar, Brechla Moreno Arévalo, Ana Paula Rodrigues, Raquel Guiomar, Vernon Jian Ming Lee, Li Wei Ang, Cheryl Cohen, Florette Treurnicht, Alla Mironenko, Olha Holubka, Joseph Bresee, Lynnette Brammer, Mai T Q Le, Phuong V M Hoang, Clotilde El Guerche-Séblain, John Paget, Global Influenza B Study team   +54 more
doaj   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Serum High-Mobility-Group Box 1 as a Biomarker and a Therapeutic Target during Respiratory Virus Infections

mBio, 2018
Host-derived “danger-associated molecular patterns” (DAMPs) contribute to innate immune responses and serve as markers of disease progression and severity for inflammatory and infectious diseases.
Mira C. Patel, Kari Ann Shirey, Marina S. Boukhvalova, Stefanie N. Vogel, Jorge C. G. Blanco   +4 more
doaj   +1 more source