Results 91 to 100 of about 367,688 (317)

Significant impact of sequence variations in the nucleoprotein on CD8 T cell-mediated cross-protection against influenza A virus infections. [PDF]

PLoS ONE, 2010
Memory CD8 T cells to influenza A viruses are widely detectable in healthy human subjects and broadly cross-reactive for serologically distinct influenza A virus subtypes.
Weimin Zhong, Feng Liu, Libo Dong, Xiuhua Lu, Kathy Hancock, Ellis L Reinherz, Jacqueline M Katz, Suryaprakash Sambhara   +7 more
doaj   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Clinical characteristics of critically ill patients co-infected with SARS-CoV-2 and the influenza virus in Wuhan, China

International Journal of Infectious Diseases, 2020
Objective: To delineate the clinical characteristics of critically ill COVID-19 patients co-infected with influenza. Methods: This study included adult patients with laboratory-confirmed COVID-19 form Tongji Hospital (Wuhan, China), with or without ...
Simin Ma, Xiaoquan Lai, Zhe Chen, Shenghao Tu, Kai Qin   +4 more
doaj   +1 more source

Influenza D Virus Infection in Feral Swine Populations, United States [PDF]

Emerging Infectious Diseases, 2018
Influenza D virus (IDV) has been identified in domestic cattle, swine, camelid, and small ruminant populations across North America, Europe, Asia, South America, and Africa. Our study investigated seroprevalence and transmissibility of IDV in feral swine. During 2012-2013, we evaluated feral swine populations in 4 US states; of 256 swine tested, 57 (19.
Ferguson, Lucas, Luo, Kaijian, Olivier, Alicia K., Cunningham, Fred L., Blackmon, Sherry, Hanson-Dorr, Katie, Sun, Hailiang, Baroch, John, Lutman, Mark W., Quade, Bianca, Epperson, William, Webby, Richard, DeLiberto, Thomas J., Wan, Xiu-Feng   +13 more
openaire   +3 more sources

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Influenza D virus M2 protein exhibits ion channel activity in Xenopus laevis oocytes. [PDF]

PLoS ONE, 2018
BACKGROUND:A new type of influenza virus, known as type D, has recently been identified in cattle and pigs. Influenza D virus infection in cattle is typically asymptomatic; however, its infection in swine can result in clinical disease. Swine can also be
Evan Kesinger, Jianing Liu, Aaron Jensen, Catherine P Chia, Andrew Demers, Hideaki Moriyama   +5 more
doaj   +1 more source

Mapping the phosphoproteome of influenza A and B viruses by mass spectrometry [PDF]

, 2012
Protein phosphorylation is a common post-translational modification in eukaryotic cells and has a wide range of functional effects. Here, we used mass spectrometry to search for phosphorylated residues in all the proteins of influenza A and B viruses ...
Denham, Eleanor M., Fodor, Ervin, Hester, Svenja S., Hutchinson, Edward C., Ridlova, Gabriela, Thomas, Benjamin, Trudgian, David C., Turrell, Lauren, York, Ashley   +8 more
core   +3 more sources

Persistent Leukoencephalopathy Following H1N1 Infection Associated With a Novel MYRF Variant (p.Gly735Asp)

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Mutations in myelin regulatory factor (MYRF) are linked to demyelinating disorders. We report a 38‐year‐old male who developed acute symmetric leukoencephalopathy mimicking a stroke following an influenza A virus infection. While clinical symptoms markedly improved with corticosteroids, MRI revealed persistent white matter lesions, contrasting
Jinghan Hu, Leiyun Huang, Wan Zhu, Min Peng, Qiang Gong, Jing Qian   +5 more
wiley   +1 more source

Comparison of Pathogenicity and Transmissibility of Influenza B and D Viruses in Pigs

Viruses, 2019
Influenza viruses are important pathogens causing respiratory disease in humans and animals. In contrast to influenza A virus (IAV) that can infect a wide range of animal species, other influenza viruses, including influenza B virus (IBV), influenza C ...
Jinhwa Lee, Liping Wang, Rachel Palinski, Tim Walsh, Dongchang He, Yonghai Li, Rui Wu, Yuekun Lang, Sun-Young Sunwoo, Juergen A. Richt, Wenjun Ma   +10 more
doaj   +1 more source

Detection of Influenza D Virus among Swine and Cattle, Italy [PDF]

Emerging Infectious Diseases, 2016
To the Editor: Recent studies have identified a new genus of the Orthomyxoviridae family (1–5). The virus, distantly related to human influenza C virus, has been provisionally designated as influenza D virus. This novel virus was identified for the first time in pigs with influenza-like illness (1), but subsequent serologic and virologic surveys have ...
Chiara Chiapponi, Silvia Faccini, Aurora De Mattia, Laura Baioni, Ilaria Barbieri, Carlo Rosignoli, Arrigo Nigrelli, Emanuela Foni   +7 more
openaire   +3 more sources