Results 231 to 240 of about 367,688 (317)

Mutations flanking the carbohydrate binding site of surfactant protein D confer antiviral activity for pandemic influenza A viruses

open access: green, 2014
Nikolaos M. Nikolaidis   +10 more
openalex   +1 more source

First isolation of influenza D virus from cattle in Northeast China. [PDF]

open access: yesMicrobiol Spectr
Gao H   +9 more
europepmc   +1 more source

A Modular Vaccine Platform Against SARS‐CoV‐2 Based on Self‐Assembled Protein Nanoparticles

open access: yesAdvanced Science, EarlyView.
A modular BP26 nanoparticle vaccine platform incorporating the SpyTag/SpyCatcher system enables high‐density, repetitive antigen display with post‐expression flexibility. Conjugation of the SARS‐CoV‐2 RBD to BP26 nanoparticles elicits strong humoral immunity and confers protection against viral challenge in vivo.
Seojung Lee   +6 more
wiley   +1 more source

Rapid evolution leads to extensive genetic diversification of cattle flu Influenza D virus. [PDF]

open access: yesCommun Biol
Limaye S   +6 more
europepmc   +1 more source

CRISPR in MOF Formulation with Enhanced Stability, Activity, and Altered PAM Specificity for Broad‐Spectrum Diagnosis of Bacterial Sepsis

open access: yesAdvanced Science, EarlyView.
CRISPR‐FLEXMO (CRISPR with flexible PAM in MOF encapsulation) integrates a PAM‐relaxed Cas12a K607R enzyme with a manganese‐coordinated MOF for broad‐spectrum diagnosis of bacterial sepsis. The MOF enhances activity and preserves functionality under heat, solvent, and chaotropic stress, supporting long‐term room‐temperature storage.
Tathagata Pal   +3 more
wiley   +1 more source

Behavior‐ and Cell Type‐Specific Cortico‐Striatal Decoupling in a Parkinson's Disease‐Like Mouse Model

open access: yesAdvanced Science, EarlyView.
Utilizing dual‐site fiber photometry, this study examines cortico‐striatal coupling with cell type resolution, identifying behavior‐ and cell type‐specific cortico striatal decoupling and its dopamine‐dependent mechanism in a Parkinson's disease mouse model.
Xu‐Ran Yao   +4 more
wiley   +1 more source

Serological Evidence for Circulation of Influenza D Virus in the Ovine Population in Italy. [PDF]

open access: yesPathogens
Lanave G   +12 more
europepmc   +1 more source

DNA Nanostructure‐Templated Multivalency Enables Broad‐Spectrum Virus Inhibition

open access: yesAdvanced Science, EarlyView.
A honeycomb‐shaped DNA nanostructure is introduced that organizes nanobodies or aptamers into trimeric clusters mirroring the native hemagglutinin arrangement on influenza viruses. This geometry‐matched multivalency enhances binding avidity by up to 1000‐fold, resulting in robust, broad‐spectrum viral neutralization and a 30–55% improvement in host ...
Saurabh Umrao   +8 more
wiley   +1 more source

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