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The Quest for a Truly Universal Influenza Vaccine
There is an unmet public health need for a universal influenza vaccine (UIV) to provide broad and durable protection from influenza virus infections. The identification of broadly protective antibodies and cross-reactive T cells directed to influenza ...
Y. Jang, B. Seong
semanticscholar +1 more source
Roadblocks to translational challenges on viral pathogenesis. [PDF]
Distinct roadblocks prevent translating basic findings in viral pathogenesis into therapies and implementing potential solutions in the clinic. An ongoing partnership between the Volkswagen Foundation and Nature Medicine resulted in an interactive ...
Deeks, Steven +4 more
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IntroductionThe 2011-12 trivalent influenza vaccine contains a strain of influenza B/Victoria-lineage viruses. Despite free provision of influenza vaccine among target populations, an epidemic predominated by influenza B/Yamagata-lineage viruses occurred
Yi-Chun Lo +12 more
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Healthcare workers (HCWs) are at increased risk of exposure to the influenza virus in their daily clinical and disease prevention activities, making them a high-risk group for influenza infection.
Yuwei Liu +5 more
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Interim Estimates of 2017–18 Seasonal Influenza Vaccine Effectiveness — United States, February 2018
In the United States, annual vaccination against seasonal influenza is recommended for all persons aged ≥6 months (1). During each influenza season since 2004-05, CDC has estimated the effectiveness of seasonal influenza vaccine to prevent laboratory ...
B. Flannery +17 more
semanticscholar +1 more source
Background and Aims Influenza is one of the most widespread respiratory infections and poses a huge burden on health care worldwide. Vaccination is key to preventing and controlling influenza.
Zhengyu Zhang +6 more
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Being vigilant of the potential for an influenza pandemic, the Global Action Plan for Influenza Vaccines (GAP) promoted the establishment and maintenance of local vaccine manufacturing capacity.
Punnee Pitisuttithum, Ponthip Wirachwong
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Pandemic Influenza Vaccines [PDF]
Since their compositions remain uncertain, universal pandemic vaccines are yet to be created. They would aim to protect globally against pandemic influenza viruses that have not yet evolved. Thus they differ from seasonal vaccines to influenza virus, which are updated annually in spring to incorporate the latest circulating viruses, and are then ...
Lauren J. DiMenna, Hildegund C. J. Ertl
openaire +3 more sources
The 2017–2018 seasonal influenza epidemics were severe in the US and Australia where the A(H3N2) subtype viruses predominated. Although circulating A(H3N2) viruses did not differ antigenically from that recommended by the WHO for vaccine production ...
I. Barr +7 more
semanticscholar +1 more source
Novel Platforms for the Development of a Universal Influenza Vaccine
Despite advancements in immunotherapeutic approaches, influenza continues to cause severe illness, particularly among immunocompromised individuals, young children, and elderly adults.
A. Kumar, T. Meldgaard, S. Bertholet
semanticscholar +1 more source

