Results 101 to 110 of about 282,997 (350)

Determinants of adults' intention to vaccinate against pandemic swine flu [PDF]

, 2011
This article has been made available through the Brunel Open Access Publishing Fund.This article has been made available through the Brunel Open Access Publishing Fund.Background: Vaccination is one of the cornerstones of controlling an influenza ...
A Bandura, A Morice, AE Tozzi, BM Kuehn, C Briggs, C Cheng, CJ Armitage, CJ Armitage, CL Wong, D Hine, D Murray, D Trafimow, F Ahmed, I Ajzen, IM Rosenstock, JR Smith, JS Chor, KA Cameron, KM Cummings, LB Myers, Lynn B Myers, M Connor, P Hebert, P Watson, R Goodwin, R Povey, RC Palmer, RG Brubaker, Robin Goodwin, S Frost, S Gallagher, T Sandberg   +31 more
core   +3 more sources

A Rationally Engineered Spleen‐Tropic One‐Component Lipid‐mRNA Complex (OncoLRC) for Cancer Vaccines

Advanced Science, EarlyView.
OncoLRC, a one‐component lipid‐mRNA complex, enables efficient spleen‐targeted delivery at an exceptionally low lipid‐to‐mRNA mass ratio (1.5:1), robustly activates immune responses, inhibits tumor growth, and synergizes with checkpoint blockade, presenting a next‐generation platform for mRNA vaccines.
Qimeng Yin, Chenchen Zhang, Jiahao Li, Kun Huang, Min Qiu   +4 more
wiley   +1 more source

Co-Delivery of M2e Virus-Like Particles with Influenza Split Vaccine to the Skin Using Microneedles Enhances the Efficacy of Cross Protection

Pharmaceutics, 2019
It is a high priority to develop a simple and effective delivery method for a cross-protective influenza vaccine. We investigated skin immunization by microneedle (MN) patch with human influenza split vaccine and virus-like particles containing ...
Min-Chul Kim, Ki-Hye Kim, Jeong Woo Lee, Yu-Na Lee, Hyo-Jick Choi, Yu-Jin Jung, Yu-Jin Kim, Richard W. Compans, Mark R. Prausnitz, Sang-Moo Kang   +9 more
doaj   +1 more source

Vaccine Epidemiology and Decision-Making: A Bryant Student Focus [PDF]

, 2018
The Centers for Disease Control and Prevention estimate that influenza has resulted in between 9.2 and 35.6 million illnesses and between 12,000 and 56,000 deaths annually since 2010 (1).
Coburn, Hannah
core   +1 more source

Overview of Serological Techniques for Influenza Vaccine Evaluation: Past, Present and Future [PDF]

, 2014
Serological techniques commonly used to quantify influenza-specific antibodies include the Haemagglutination Inhibition (HI), Single Radial Haemolysis (SRH) and Virus Neutralization (VN) assays.
Callow, Calza, Chan, Cosma, De Jong, Farrohi, Ferrara, Fox, Frank, Fulton, Gross, Halloran, Harmon, Hierholzer, Johansson, Johansson, Kendal, Kilbourne, Montomoli, Okuno, O’Neill, Powers, Probert, Rowe, Schild, Schulman, Schulman, Scott, Sylte, Van Assen, Yewdell   +30 more
core   +3 more sources

Payload‐Driven Design of Polymeric Carriers for Nucleic Acid Delivery: Insights from Structure–Function Relationships

Advanced Science, EarlyView.
Polymeric carriers provide versatile platforms for nucleic acid delivery. This review introduces a novel perspective inspired by protein structural organization to explore structure–function relationships of polymeric carriers, highlighting requirements of different nucleic acid payloads.
Hanieh Moradian, Charlotte Maeve Dunne, Manfred Gossen, Matthias Hartlieb   +3 more
wiley   +1 more source

Genetically‐Programmed Hypervesiculation of Lactiplantibacillus Plantarum Increases Production of Bacterial Extracellular Vesicles with Therapeutic Efficacy in a Preclinical Inflammatory Bowel Disease Model

Advanced Science, EarlyView.
The development of a novel engineered strain of Lactiplantibacillus plantarum (Lp) is reported that can produce bacterial extracellular vesicles (BEVs) at >60‐fold higher yields than the unmodified parental strain. These Lp BEVs retain therapeutic bioactivity as validated in a mouse model of dextran sodium sulfate‐induced colitis.
Nicholas H Pirolli, Daniel Levy, Alyssa Schledwitz, Natalia Sampaio Moura, Mitali Sarkar, Talia J. Solomon, Emily H. Powsner, Raith Nowak, Zuzanna Mamczarz, Christopher J. Bridgeman, Sulayman Khan, Andrew Hui, Nidhi Anne, Laura Reus, William E. Bentley, Jean‐Pierre Raufman, Steven M. Jay   +16 more
wiley   +1 more source

Bacteriophage‐Mimetic DNA Origami Needle for Targeted Membrane Penetration and Cytosolic Cargo Delivery

Advanced Science, EarlyView.
We designed a synthetic DNA origami needle‐like structure inspired by bacteriophages for targeted drug delivery. Functionalized with trastuzumab antibodies, cholesterol, and dyes, it selectively targets SKBR3 cancer cells. A glutathione‐triggered dye payload enables controlled release, and delivery is verified using confocal microscopy and live cell ...
Anirban Samanta, Mette Galsgaard Malle, Emily Tsang, Marjan Omer, Mads K. Skaanning, Sarah Youssef, Jørgen Kjems, Kurt V. Gothelf   +7 more
wiley   +1 more source

Coverage and determinants of influenza vaccine among pregnant women: a cross-sectional study

BMC Public Health, 2019
Background Pregnant women are at increased risk of influenza-related complications. The World Health Organisation recommends influenza vaccination to this high-risk population as highest priority.
Vittoria Offeddu, Clarence C. Tam, Tze Tein Yong, Lay Kok Tan, Koh Cheng Thoon, Nicole Lee, Thiam Chye Tan, George S. H. Yeo, Chee Fu Yung   +8 more
doaj   +1 more source

Safety and immunogenicity of a novel quadrivalent subunit influenza vaccine in animal models

Human Vaccines & Immunotherapeutics, 2020
Background: Compared with trivalent influenza vaccines, quadrivalent influenza vaccines are expected to provide wider protection against influenza B virus infections. We developed a novel quadrivalent subunit influenza vaccine which was distinct from the
Huayue Ye, Siyue Jia, Yuhui Zhang, Jingxin Li, Fengcai Zhu   +4 more
doaj   +1 more source