Results 121 to 130 of about 885,970 (344)

Models for predicting the evolution of influenza to inform vaccine strain selection

open access: yesHuman Vaccines & Immunotherapeutics, 2018
Influenza vaccine composition is reviewed before every flu season because influenza viruses constantly evolve through antigenic changes. To inform vaccine updates, laboratories that contribute to the World Health Organization Global Influenza ...
Joseph K. Agor, Osman Y. Özaltın
doaj   +1 more source

Influenza vaccines and immunopathology [PDF]

open access: yesExpert Review of Vaccines, 2012
“…the concern over immunopathology resulting from T-cell responses to nucleoprotein or other conserved antigens in the absence of neutralizing antibodies in humans can be narrowed to high-dose infections with some pandemic viruses, although both in 1918 and 2009, there is evidence that T-cell responses were more likely to be responsible for protection ...
openaire   +3 more sources

Efforts to Improve the Seasonal Influenza Vaccine

open access: yesVaccines, 2018
Influenza viruses infect approximately 20% of the global population annually, resulting in hundreds of thousands of deaths. While there are Food and Drug Administration (FDA) approved antiviral drugs for combating the disease, vaccination remains the ...
Alfred T. Harding, Nicholas S. Heaton
semanticscholar   +1 more source

Respiratory virus mRNA vaccines: mRNA Design, clinical studies, and future challenges

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Abstract Respiratory infectious diseases frequently erupt on a global scale, with RNA viruses, such as SARS‐CoV‐2, RSV, and influenza viruses, posing challenges to vaccine development due to their high mutation rates. Traditional vaccine development cycles are lengthy and struggle to keep pace with rapidly evolving viruses, whereas messenger RNA (mRNA)
Linlin Zheng, Han Feng
wiley   +1 more source

Influenza vaccination in Korea

open access: yesJournal of Infection, 2014
open
Jae Kwan Jun   +3 more
openaire   +4 more sources

Graphene Oxide‐Based Gene Modulation in Preferential Elimination of Lung Cancer Cells in a 3D Tumor Microenvironment Model

open access: yesAdvanced NanoBiomed Research, EarlyView.
Chemically modified graphene oxide nanocarriers provide a targeted lung cancer gene therapy platform. In a 3D tumor microenvironment model, these nanocarriers deliver therapeutic genes, regulate immune markers, and induce apoptosis in cancer cells. Combined gene delivery enhances cancer cell elimination, demonstrating the potential of this approach for
Francesca Grilli   +3 more
wiley   +1 more source

Influenza epidemiology and vaccine effectiveness among patients with influenza-like illness, viral watch sentinel sites, South Africa, 2005-2009.

open access: yesPLoS ONE, 2014
BackgroundThere is limited data on the epidemiology of influenza and few published estimates of influenza vaccine effectiveness (VE) from Africa. In April 2009, a new influenza virus strain infecting humans was identified and rapidly spread globally.
Genevie M Ntshoe   +11 more
doaj   +1 more source

Development of Universal Influenza Vaccines Targeting Conserved Viral Proteins

open access: yesVaccines, 2019
Vaccination is still the most efficient way to prevent an infection with influenza viruses. Nevertheless, existing commercial vaccines face serious limitations such as availability during epidemic outbreaks and their efficacy. Existing seasonal influenza
Seyed Davoud Jazayeri, Chit Laa Poh
doaj   +1 more source

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