Results 141 to 150 of about 885,970 (344)

Minimizing batch‐to‐batch variability of a live virus vaccine by process analytical technologies

open access: yesBiotechnology Progress, EarlyView.
Abstract For bioprocesses producing live virus, such as enterovirus Coxsackievirus A21, viral titer (infectivity basis) decay rates can exceed 30% within a day. Consequently, harvest timing is paramount. To optimize titer at harvest, a continuous viral product titer model was generated to elucidate kinetics.
Katherine Forrester   +4 more
wiley   +1 more source

Influenza Vaccine

open access: yes, 2021
The influenza virus circulates continuously, causing regional epidemics and outbreaks, leading to thousands of deaths. For instance, according to the Centers for Disease Control and Prevention (CDC) data statistics, more than 13 million flu cases were recorded so far in the 2019-20 timeframe.
openaire   +1 more source

Promising Prodiginins Biological Activities

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto   +6 more
wiley   +1 more source

Comparison of the post-marketing safety profile between influenza and COVID-19 vaccines: An analysis of the vaccine adverse event reporting system

open access: yesSaudi Pharmaceutical Journal, 2022
The global coronavirus disease (COVID-19) epidemic can be partially managed by vaccines; however, the public must be informed about the safety of COVID-19 vaccines to avoid hesitancy.
Abdullah K. Al-Ahmari   +7 more
doaj  

Ethnomedicinal Uses, Phytochemistry, Pharmacological Activities, and Toxicology of the Subfamily Gomphrenoideae (Amaranthaceae): A Comprehensive Review

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves   +3 more
wiley   +1 more source

Structure−Activity Relationships of New 1‐Aryl‐1H‐Indole Derivatives as SARS‐CoV‐2 Nsp13 Inhibitors

open access: yesChemMedChem, EarlyView.
SARS‐CoV‐2 nsp13 is a promising target to develop effective antivirals. Pursuing the studies, new indolyl derivatives to deepen SARs are designed. The newly synthesized N‐aryl indoles are active vs both nsp13‐associated activities. They exert antiviral activity vs SARS‐CoV‐2 infected cells with no cytotoxicity.
Valentina Noemi Madia   +18 more
wiley   +1 more source

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