Results 51 to 60 of about 635,953 (258)

Intervensi Model Pendidikan dan Komunitas tentang Influenza Menurut Mahasiswa Kedokteran dan Keperawatan

Jurnal Pendidikan Kedokteran Indonesia, 2016
Background: Medical awareness and clinical management of seasonal influenza remains limited in Indonesia. As future health workers, nursing students’ and medical students’ knowledge, attitude, and practice regarding influenza and influenza vaccine are ...
Andyana Sabtisan, Priska Yunianti, Bryani Titi Santi, Dwi Jani Juliawati, Elisabeth Rukmini   +4 more
doaj   +1 more source

WT1‐Targeted Oral Bifidobacterium longum Vaccine Enhances Checkpoint Blockade Efficacy in Pancreatic Cancer

Advanced Science, EarlyView.
Oral WT1‐targeted Bifidobacterium longum vaccine promotes WT1‐associated cellular immunity and enhances anti‐PD‐1/anti‐CTLA‐4 efficacy in pancreatic cancer. ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains largely unresponsive to immune checkpoint inhibitors (ICI) due to its profoundly immunosuppressive tumor microenvironment.
Taiki Yamazaki, Aori Minami, Misako Hirota, Mirei Hirano, Ryota Sato, Atsuki Honma, Hideto Ueki, Toshiro Shirakawa   +7 more
wiley   +1 more source

Post-pandemic seroprevalence of pandemic influenza A (H1N1) 2009 infection (swine flu) among children <18 years in Germany. [PDF]

, 2011
We determined antibodies to the pandemic influenza A (H1N1) 2009 virus in children to assess: the incidence of (H1N1) 2009 infections in the 2009/2010 season in Germany, the proportion of subclinical infections and to compare titers in vaccinated and ...
Thomas Mertens, Andrea Streng, Niehues Tim, Stephan Wirth, Rüdiger von Kries, Hampl, Walter, Michel, Detlef, Shai, Sonu, Falkenhorst, Gerhard, Kaiser, Petra, Weiss Susanne, von Kries, Rüdiger, Walter Hampl, Schroten Horst, König, Carl-Heinz Wirsing von, Tenenbaum, Tobias, Niehues, Tim, Peters, Jochen, Carl Heinz Wirsing von König, Tobias Tenenbaum, Susanne Weiss, Petra Kaiser, Wirsing von Koenig, Carl Heinz, Hans-Iko Huppertz, Ellen Kuscher, Mertens Thomas, Hermann Girschick, Weiss, Susanne, Wirsing von König, Carl-Heinz, Tim Niehues, Huppertz, Hans-Iko, Simon Rückinger, Streng, Andrea, Kries, Rüdiger von, Kaiser Petra, Horst Schroten, Sonu Shai, Falkenhorst Gerhard, Wirsing von König Carl Heinz, Axel Sauerbrey, Liese, Johannes, Johannes Liese, Mertens, Thomas, Rückinger Simon, Hampl Walter, Schroten, Horst, Sauerbrey, Axel, Gerhard Falkenhorst, Shai Sonu, Huppertz Hans-Iko, von Kries Rüdiger, Rückinger, Simon, Tenenbaum Tobias, Jochen Peters, Wirth Stephan, Liese Johannes, Girschick, Hermann, Peters Jochen, Michel Detlef, Streng Andrea, Sauerbrey Axel, Wirth, Stephan, Kuscher Ellen, Detlef Michel, Girschick Hermann, Kuscher, Ellen   +65 more
core   +2 more sources

Stabilization of influenza vaccine enhances protection by microneedle delivery in the mouse skin.

PLoS ONE, 2009
BackgroundSimple and effective vaccine administration is particularly important for annually recommended influenza vaccination. We hypothesized that vaccine delivery to the skin using a patch containing vaccine-coated microneedles could be an attractive ...
Fu-Shi Quan, Yeu-Chun Kim, Dae-Goon Yoo, Richard W Compans, Mark R Prausnitz, Sang-Moo Kang   +5 more
doaj   +1 more source

Porcine Deltacoronavirus M Protein Binds NLRP3 to Promote Inflammasome Assembly via Competition with TRIM31

Advanced Science, EarlyView.
Porcine deltacoronavirus (PDCoV) infection induces severe intestinal inflammation and acute diarrhea in piglets, yet the molecular mechanism remains incompletely understood. The M protein activates NLRP3 inflammasome through dual mechanisms: direct binding to the NLRP3 LRR domain and disruption of TRIM31‐mediated K48‐linked ubiquitination.
Jinhui Hou, Fangfang Han, Anqi Liu, Yang Yu, Rui Zhao, Zhengting Shi, Yanrong Lv, Jinli Liu, Shaopo Zu, Zhanyong Wei, Jin Yuan, Hui Hu   +11 more
wiley   +1 more source

Estimating the Impact of Influenza Vaccination on Acute and ICU Hospital Bed Usage in an Influenza Season under Endemic COVID-19 in the US

Vaccines, 2022
In 2021–2022, influenza vaccine coverage in the US dropped below pre-COVID-19 pandemic levels. Cocirculation of COVID-19 and influenza could place a substantial burden on hospital utilization in future seasons, particularly given the reduced exposure to ...
Van Hung Nguyen, Joaquin F. Mould-Quevedo   +1 more
doaj   +1 more source

A Spatially Directed Microneedle Patch Enables Intratumoral Co‐Delivery of FOLFIRINOX, Surufatinib, and Anti‐PD‐1 for Chemo‐Immunotherapy of Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
A double‐layered shell‐core microneedle patch is developed to co‐deliver FOLFIRINOX, surufatinib, and anti‐PD‐1 for localized chemo‐immunotherapy of PDAC. This strategy achieves sustained tumor suppression, reduces metastasis, and reprograms the TME by enhancing CD8+ T‐cell infiltration and inhibiting Tregs and M2 macrophages infiltration, while ...
Tingting Kong, Ximo Xu, Xiao Zhang, Chuntao Wu, Zhengjun Qiu, Beiyuan Hu, Zihao Qi, Qiang Tian, Yuqin Yang, Hanguang Dong, Fei Wu, Tuo Jin, Yan Zheng, Jiang Long   +13 more
wiley   +1 more source

Knowledge, attitudes, barriers and uptake rate of influenza virus vaccine among adults with chronic diseases in Jordan: a multicentric cross-sectional study

Frontiers in Public Health
BackgroundSeasonal Influenza is a major cause of morbidity and mortality worldwide. Despite the well-established preventive role of the influenza vaccine particularly for patients at high risk, influenza vaccine uptake remains suboptimal. In Jordan, data
Munir Abu-Helalah, Munir Abu-Helalah, Tarek Gharibeh, Mohammad Al-Hanaktah, Islam Khatatbeh, Fadi Batarseh, Amro Asfour, Omar Okkeh, Abdallah Dalal, Ahmad Alhendi, Huthaifa Ababneh   +10 more
doaj   +1 more source

Effectiveness of A(H1N1)pdm09 influenza vaccine in adults recommended for annual influenza vaccination. [PDF]

PLoS ONE, 2013
INTRODUCTION: Because of variability in published A(H1N1)pdm09 influenza vaccine effectiveness estimates, we conducted a study in the adults belonging to the risk groups to assess the A(H1N1)pdm09 MF59-adjuvanted influenza vaccine effectiveness. METHODS:
Giedre Gefenaite, Margot Tacken, Jens Bos, Irina Stirbu-Wagner, Joke C Korevaar, Ronald P Stolk, Bert Wolters, Marc Bijl, Maarten J Postma, Jan Wilschut, Kristin L Nichol, Eelko Hak   +11 more
doaj   +1 more source

Acceptance of influenza vaccination and associated factors among teachers in China: A cross-sectional study based on health belief model

Human Vaccines & Immunotherapeutics, 2023
Teachers played an important role on the transmission of influenza in schools and communities. The study aims to investigate the influenza vaccination coverage and the factors determining flu vaccination acceptance among teachers in Hangzhou, China.
Wenwen Gu, Yan Liu, Qinghua Chen, Jun Wang, Xinren Che, Jian Du, Xiaoping Zhang, Yuyang Xu, Xuechao Zhang, Wei Jiang, Jing Wang, Qixin Xie, Zhaojun Lu, Yingying Yang, Lintao Gu, Junfang Chen   +15 more
doaj   +1 more source