Results 11 to 20 of about 225,025 (354)

Influenza and Memory T Cells: How to Awake the Force [PDF]

Vaccines, 2016
Annual influenza vaccination is an effective way to prevent human influenza. Current vaccines are mainly focused on eliciting a strain-matched humoral immune response, requiring yearly updates, and do not provide protection for all vaccinated individuals ...
Jan Spitaels, Kenny Roose, Xavier Saelens   +2 more
doaj   +4 more sources

DNA Vaccines Encoding Antigen Targeted to MHC Class II Induce Influenza-Specific CD8+ T Cell Responses, Enabling Faster Resolution of Influenza Disease [PDF]

, 2016
Current influenza vaccines are effective but imperfect, failing to cover against emerging strains of virus and requiring seasonal administration to protect against new strains. A key step to improving influenza vaccines is to improve our understanding of
Laura Lambert, Ekaterina Kinnear, Jacqueline U. McDonald, Gunnveig Grødeland, Bjarne Bogen, Elisabeth Stubsrud, Mona M. Lindeberg, Agnete B. Fredriksen, John S. Tregoning   +8 more
core   +10 more sources

Low dose influenza virus challenge in the ferret leads to increased virus shedding and greater sensitivity to oseltamivir [PDF]

, 2014
Ferrets are widely used to study human influenza virus infection. Their airway physiology and cell receptor distribution makes them ideal for the analysis of pathogenesis and virus transmission, and for testing the efficacy of anti-influenza ...
Barclay, Wendy S., Bean, Thomas J., Bruce, Christine, Carroll, Miles W., Dimmock, N. J., Dove, Brian K., Dowall, Stuart, Easton, A. J. (Andrew J.), Hallis, Bassam, Marriott, Anthony C., Newman, Edmund, Pearson, Geoff, Plank, Jenna, Rayner, Emma, Ryan, Kathryn A., Silman, Nigel J., Taylor, Irene, Whittaker, Catherine J.   +17 more
core   +9 more sources

Haemagglutination inhibition and virus microneutralisation serology assays: use of harmonised protocols and biological standards in seasonal influenza serology testing and their impact on inter-laboratory variation and assay correlation: A FLUCOP collaborative study

Frontiers in Immunology, 2023
IntroductionThe haemagglutination inhibition assay (HAI) and the virus microneutralisation assay (MN) are long-established methods for quantifying antibodies against influenza viruses. Despite their widespread use, both assays require standardisation to
Joanna Waldock, Edmond J. Remarque, Lingyi Zheng, Sammy Ho, Katja Hoschler, Britta Neumann, Hanna Sediri-Schön, Claudia M. Trombetta, Emanuele Montomoli, Serena Marchi, Giulia Lapini, Fan Zhou, Sarah L. Lartey, Rebecca J. Cox, Marzia Facchini, Maria Rita Castrucci, Damien Friel, Thierry Ollinger, Catherine Caillet, Nedzad Music, Giuseppe Palladino, Othmar G. Engelhardt, the FLUCOP consortium   +22 more
doaj   +1 more source

Agent-based model of the impact of higher influenza vaccine efficacy on seasonal influenza burden

Vaccine: X, 2023
Introduction: Current influenza vaccines have limited effectiveness. COVID-19 vaccines using mRNA technology have demonstrated very high efficacy, suggesting that mRNA vaccines could be more effective for influenza. Several such influenza vaccines are in
Mary G. Krauland, Richard K. Zimmerman, Katherine V. Williams, Jonathan M. Raviotta, Lee H. Harrison, John V. Williams, Mark S. Roberts   +6 more
doaj   +1 more source

Influenza Viruses and Vaccines: The Role of Vaccine Effectiveness Studies for Evaluation of the Benefits of Influenza Vaccines

Vaccines, 2022
Influenza is a vaccine preventable disease and vaccination remains the most effective method of controlling the morbidity and mortality of seasonal influenza, especially with respect to risk groups.
Claudia Maria Trombetta, Otfried Kistner, Emanuele Montomoli, Simonetta Viviani, Serena Marchi   +4 more
doaj   +1 more source

Engineered Nanoparticulate Vaccines to Combat Recurring and Pandemic Influenza Threats

Advanced NanoBiomed Research, 2022
Recurring seasonal flu epidemics and occasional pandemics are among the most severe threats to public health. Current seasonal influenza vaccines provide limited protection against drifted circulating strains and no protection against influenza pandemics.
Chunhong Dong, Bao-Zhong Wang
doaj   +1 more source

Public Interest in Distribution and Determinants of Influenza and Pneumonia Vaccination during the COVID-19 Pandemic: An Infodemiology and Cross-Sectional Study from China

Vaccines, 2021
Background: Following the COVID-19 pandemic, global interest in influenza vaccines and pneumonia vaccines has increased significantly. We aimed to examine public interest in and actual market circulation of influenza and pneumonia vaccines before and ...
Liubing Gong, Xu Zhang, Zhiqiang Qu, Mark R. Francis, Kaiyi Han, Cuilin Xu, Enmao Cai, Huilin Shi, Zhiyuan Hou   +8 more
doaj   +1 more source

Chemical-free inactivated whole influenza virus vaccine prepared by ultrashort pulsed laser treatment [PDF]

, 2014
There is an urgent need for rapid methods to develop vaccines in response to emerging viral pathogens. Whole inactivated virus (WIV) vaccines represent an ideal strategy for this purpose; however, a universal method for producing safe and immunogenic ...
Achilefu, Samuel, Chen, Alexander, Donthi, Nisha, Hsieh, Wen-Han, Hung, Chien-Fu, Knoff, Jayne, La, Victor, Li, Yen-Der, Tsen, Kong-Thon, Tsen, Shaw-Wei David, Wu, Tzyy-Choou   +10 more
core   +2 more sources

Animal Models Utilized for the Development of Influenza Virus Vaccines

Vaccines, 2021
Animal models have been an important tool for the development of influenza virus vaccines since the 1940s. Over the past 80 years, influenza virus vaccines have evolved into more complex formulations, including trivalent and quadrivalent inactivated ...
Ericka Kirkpatrick Roubidoux, Stacey Schultz-Cherry   +1 more
doaj   +1 more source