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Nucleoprotein as a Promising Antigen for Broadly Protective Influenza Vaccines
Vaccines, 2023 Annual vaccination is considered as the main preventive strategy against seasonal influenza. Due to the highly variable nature of major viral antigens, such as hemagglutinin (HA) and neuraminidase (NA), influenza vaccine strains should be regularly ...
A. Rak, I. Isakova-Sivak, L. Rudenko
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Animal Models Utilized for the Development of Influenza Virus Vaccines
Vaccines, 2021 Animal models have been an important tool for the development of influenza virus vaccines since the 1940s. Over the past 80 years, influenza virus vaccines have evolved into more complex formulations, including trivalent and quadrivalent inactivated ...
Ericka Kirkpatrick Roubidoux +1 more
doaj +2 more sources
Cross-protection against highly pathogenic avian influenza H5N1 virus from seasonal influenza vaccines: a systematic review and meta-analysis of ferret studies [PDF]
Emerging Microbes and InfectionsThe recent surge in spillover events of highly pathogenic avian influenza A(H5N1) clade 2.3.4.4b to humans and mammals in North America has raised urgent pandemic concerns. Human H5N1 vaccines are unavailable in most countries.
IShin Tseng +5 more
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Development of Universal Influenza Vaccines Targeting Conserved Viral Proteins [PDF]
Vaccines, 2019 Vaccination is still the most efficient way to prevent an infection with influenza viruses. Nevertheless, existing commercial vaccines face serious limitations such as availability during epidemic outbreaks and their efficacy. Existing seasonal influenza
S. D. Jazayeri, C. Poh
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Vaccines, 2021 Two reviews by Harding and Heaton [...]
Effie-Photini Tsilibary +2 more
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Advances in Adjuvanted Influenza Vaccines
Vaccines, 2023 The numerous influenza infections that occur every year present a major public health problem. Influenza vaccines are important for the prevention of the disease; however, their effectiveness against infection can be suboptimal.
Shintaro Shichinohe, Tokiko Watanabe
semanticscholar +1 more source
Vaccine, 2009 Influenza A viruses pose a substantial threat to the human population whether by purposeful manipulation and release or by the natural process of interspecies transmissions from animal reservoirs. The challenge with preparing for these events with vaccination strategies is that the best forms of protective immunity target the most variable of the viral
A H, Ellebedy, R J, Webby
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Influenza and the influenza vaccine [PDF]
Canadian Medical Association Journal, 2007 Influenza, or the “flu,” is an infection caused by the influenza virus. The virus infects the nose and throat, and it can sometimes spread to the lungs. Influenza commonly causes acute fever, cough, chills, tiredness, body aches and, in young children, ear aches.
Noni, MacDonald +2 more
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MMWR Recommendations and Reports, 2023 Summary This report updates the 2022–23 recommendations of the Advisory Committee on Immunization Practices (ACIP) concerning the use of seasonal influenza vaccines in the United States ( MMWR Recomm Rep 2022;71[No. RR-1]:1–28).
L. Grohskopf +5 more
semanticscholar +1 more source