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Animal Models Utilized for the Development of Influenza Virus Vaccines
Animal models have been an important tool for the development of influenza virus vaccines since the 1940s. Over the past 80 years, influenza virus vaccines have evolved into more complex formulations, including trivalent and quadrivalent inactivated ...
Ericka Kirkpatrick Roubidoux +1 more
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Adjuvantation of Influenza Vaccines to Induce Cross-Protective Immunity [PDF]
Influenza poses a huge threat to global public health. Influenza vaccines are the most effective and cost-effective means to control influenza. Current influenza vaccines mainly induce neutralizing antibodies against highly variable globular head of ...
Zhuofan Li +3 more
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Adenoviral Vector-Based Vaccine Platforms for Developing the Next Generation of Influenza Vaccines
Ever since the discovery of vaccines, many deadly diseases have been contained worldwide, ultimately culminating in the eradication of smallpox and polio, which represented significant medical achievements in human health.
Ekramy E. Sayedahmed +4 more
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Nurses have an important part to play in dispelling myths about influenza vaccination and in actively encouraging older people to attend for vaccination. Irene Schofield discusses the issues.
A, Uma, P, Thirumalaikolundusubramanian
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Two reviews by Harding and Heaton [...]
Effie-Photini Tsilibary +2 more
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IntroductionThe haemagglutination inhibition assay (HAI) and the virus microneutralisation assay (MN) are long-established methods for quantifying antibodies against influenza viruses. Despite their widespread use, both assays require standardisation to
Joanna Waldock +22 more
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Agent-based model of the impact of higher influenza vaccine efficacy on seasonal influenza burden
Introduction: Current influenza vaccines have limited effectiveness. COVID-19 vaccines using mRNA technology have demonstrated very high efficacy, suggesting that mRNA vaccines could be more effective for influenza. Several such influenza vaccines are in
Mary G. Krauland +6 more
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Nucleoprotein as a Promising Antigen for Broadly Protective Influenza Vaccines
Annual vaccination is considered as the main preventive strategy against seasonal influenza. Due to the highly variable nature of major viral antigens, such as hemagglutinin (HA) and neuraminidase (NA), influenza vaccine strains should be regularly ...
Irina Isakova-Sivak +2 more
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Engineered Nanoparticulate Vaccines to Combat Recurring and Pandemic Influenza Threats
Recurring seasonal flu epidemics and occasional pandemics are among the most severe threats to public health. Current seasonal influenza vaccines provide limited protection against drifted circulating strains and no protection against influenza pandemics.
Chunhong Dong, Bao-Zhong Wang
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Influenza is a vaccine preventable disease and vaccination remains the most effective method of controlling the morbidity and mortality of seasonal influenza, especially with respect to risk groups.
Claudia Maria Trombetta +4 more
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