Results 41 to 50 of about 109,024 (308)

Immunogenicity and tolerability of an MF59-adjuvanted, egg-derived, A/H1N1 pandemic influenza vaccine in children 6-35 months of age [PDF]

, 2014
Background: Vaccines against pandemic A/H1N1 influenza should provide protective immunity in children, because they are at greater risk of disease than adults.
Abarca, Katia, Arora, Ashwani, Della Cioppa, Giovanni, Kieninger-Baum, Dorothee, Knuf, Markus, Lattanzi, Maria, Leroux-Roels, Geert, Pedotti, Paola, Rivera, Luis, Rümke, Hans C   +9 more
core   +2 more sources

Trends of influenza B during the 2010–2016 seasons in 2 regions of north and south Italy: The impact of the vaccine mismatch on influenza immunisation strategy [PDF]

, 2018
Influenza A and B viruses are responsible for respiratory infections, representing globally seasonal threats to human health. The 2 viral types often co-circulate and influenza B plays an important role in the spread of infection.
Alicino C., Ansaldi F., Calamusa G., Canepa P., Colomba G. M. E., Orsi A., Pojero F., Tramuto F., Trucchi C., Vitale F.   +9 more
core   +1 more source

Adjuvanted influenza vaccines [PDF]

Human Vaccines & Immunotherapeutics, 2012
The search for adjuvants has been stimulated by the need to ensure greater protection against influenza among subjects who show a reduced immune response to conventional influenza vaccines. Aluminum salts have long been used but are not considered satisfactory.
N. Principi, Esposito, Susanna Maria Roberta   +1 more
openaire   +7 more sources

Impact of the coronavirus disease 2019 epidemic and a free influenza vaccine strategy on the willingness of residents to receive influenza vaccines in Shanghai, China

Human Vaccines & Immunotherapeutics, 2021
The influenza vaccine is not included in China’s national immunization program. Here, we assessed influenza vaccine coverage among Shanghai residents and estimated the impacts of the coronavirus disease 2019 (COVID-19) epidemic and a hypothetical free ...
Yehong Zhou, Jing Tang, Junjie Zhang, Qiangsong Wu   +3 more
doaj   +1 more source

Recombinant Influenza Vaccines [PDF]

Acta Naturae, 2012
This review covers the problems encountered in the construction and production of new recombinant influenza vaccines. New approaches to the development of influenza vaccines are investigated; they include reverse genetics methods, production of virus-like particles, and DNA- and viral vector-based vaccines.
Sedova, E., Shcherbinin, D., Migunov, A., Smirnov, Iu, Logunov, D., Shmarov, M., Tsybalova, L., Naroditskiĭ, B., Kiselev, O., Gintsburg, A.   +9 more
openaire   +4 more sources

Substitutions near the hemagglutinin receptor-binding site determine the antigenic evolution of influenza A H3N2 viruses in U.S. swine [PDF]

, 2014
Swine influenza A virus is an endemic and economically important pathogen in pigs, with the potential to infect other host species. The hemagglutinin (HA) protein is the primary target of protective immune responses and the major component in swine ...
A. L. Vincent, Anderson, Bao, Bowman, Brown, Centers for Disease Control and Prevention, Core Team R, D. F. Burke, Darriba, De Jong, E. Skepner, Edgar, Feng, Fouchier, Garten, Gauger, Harmon, Hinshaw, Houser, Karasin, Kawaoka, Khurana, Kitikoon, Koel, Lewis, Lindstrom, Lorusso, Loving, Maddison, Miller, Montalvao, Myers, N. S. Lewis, Nelson, Nelson, Nfon, Olsen, P. Kitikoon, Paradis, Pena, Polewicz, PyMOL, Röhm, Salmon, Shinde, Skowronski, Smith, Smith, Stamatakis, T. K. Anderson, Tong, Tong, Vincent, Vincent, Vincent, Vincent, Webby, Webby, Ye   +58 more
core   +1 more source

A Decade in Review: A Systematic Review of Universal Influenza Vaccines in Clinical Trials during the 2010 Decade

Viruses, 2020
On average, there are 3–5 million severe cases of influenza virus infections globally each year. Seasonal influenza vaccines provide limited protection against divergent influenza strains.
Brigette N. Corder, Brianna L. Bullard, Gregory A. Poland, Eric A. Weaver   +3 more
doaj   +1 more source

Aged AG129 mice support the generation of highly virulent novel mouse-adapted DENV (1-4) viruses exhibiting neuropathogenesis and high lethality

Virus Research
Dengue virus infection in humans ranges from asymptomatic infection to severe infection, with ∼2.5 % overall disease fatality rate. Evidence of neurological manifestations is seen in the severe form of the disease, which might be due to the direct ...
Gazala Siddqui, Preeti Vishwakarma, Shikha Saxena, Varun Kumar, Sneh Bajpai, Amit Kumar, Satish Kumar, Ritika Khatri, Jaskaran Kaur, Sankar Bhattacharya, Shubbir Ahmed, Gulam Hussain Syed, Yashwant Kumar, Sweety Samal   +13 more
doaj   +1 more source

Incidence, Disease Severity, and Follow-Up of Influenza A/A, A/B, and B/B Virus Dual Infections in Children: A Hospital-Based Digital Surveillance Program

Viruses, 2022
Influenza virus (IV) coinfection, i.e., simultaneous infection with IV and other viruses, is a common occurrence in humans. However, little is known about the incidence and clinical impact of coinfection with two different IV subtypes or lineages (“dual ...
Patrick E. Obermeier, Lea D. Seeber, Maren Alchikh, Brunhilde Schweiger, Barbara A. Rath   +4 more
doaj   +1 more source

TIV vaccination modulates host responses to influenza virus infection that correlate with protection against bacterial superinfection [PDF]

, 2019
Background: Influenza virus infection predisposes to secondary bacterial pneumonia. Currently licensed influenza vaccines aim at the induction of neutralizing antibodies and are less effective if the induction of neutralizing antibodies is low and/or the
Choi, Angela, Christopoulou, Ioanna, García-Sastre, Adolfo, Saelens, Xavier, Schotsaert, Michael   +4 more
core   +2 more sources