Results 41 to 50 of about 968,734 (398)

Chemical-free inactivated whole influenza virus vaccine prepared by ultrashort pulsed laser treatment [PDF]

, 2014
There is an urgent need for rapid methods to develop vaccines in response to emerging viral pathogens. Whole inactivated virus (WIV) vaccines represent an ideal strategy for this purpose; however, a universal method for producing safe and immunogenic ...
Achilefu, Samuel, Chen, Alexander, Donthi, Nisha, Hsieh, Wen-Han, Hung, Chien-Fu, Knoff, Jayne, La, Victor, Li, Yen-Der, Tsen, Kong-Thon, Tsen, Shaw-Wei David, Wu, Tzyy-Choou   +10 more
core   +2 more sources

Quadrivalent influenza nanoparticle vaccines induce broad protection

Nature, 2021
Influenza vaccines that confer broad and durable protection against diverse viral strains would have a major effect on global health, as they would lessen the need for annual vaccine reformulation and immunization1.
Seyhan Boyoglu-Barnum, Daniel Ellis, Rebecca A. Gillespie, Geoffrey B. Hutchinson, Young-Jun Park, Syed M. Moin, O. Acton, Rashmi Ravichandran, M. Murphy, D. Pettie, Nicholas J Matheson, L. Carter, A. Creanga, Michael J Watson, Sally M. Kephart, S. Ataca, John R. Vaile, G. Ueda, M. Crank, L. Stewart, Kelly K. Lee, M. Guttman, D. Baker, J. Mascola, D. Veesler, B. Graham, N. King, M. Kanekiyo   +27 more
semanticscholar   +1 more source

Evaluation of the preventive effectiveness of influenza vaccines in St. Petersburg

Эпидемиология и вакцинопрофилактика, 2020
Background. The influenza vaccination coverage has steadily increased in the Russian Federation. The introduction of new domestic influenza vaccines into practice and the study of their effectiveness are of great importance for public health.
M. K. Erofeeva, M. A. Stukova, E. V. Shakhlanskaya, Zh. V. Buzitskaya, V. L. Maksakova, T. I. Krainova, T. M. Chirkina, M. M. Pisareva, D. A. Lioznov   +8 more
doaj   +1 more source

Better influenza vaccines: an industry perspective

Journal of Biomedical Sciences, 2020
Vaccination is the most effective measure at preventing influenza virus infections. However, current seasonal influenza vaccines are only protective against closely matched circulating strains.
Juine-Ruey Chen, Yo-Min Liu, Yung-Chieh Tseng, Che Ma   +3 more
semanticscholar   +1 more source

Targeting Conventional Dendritic Cells to Fine-Tune Antibody Responses

Frontiers in Immunology, 2019
Dendritic cells (DCs) facilitate cross talk between the innate and adaptive immune system. They sense and phagocytose invading pathogens, and are not only capable of activating naïve T cells, but can also determine the polarization of T cell responses ...
Demo Yemane Tesfaye, Demo Yemane Tesfaye, Arnar Gudjonsson, Arnar Gudjonsson, Bjarne Bogen, Bjarne Bogen, Bjarne Bogen, Even Fossum, Even Fossum   +8 more
doaj   +1 more source

Data and product needs for influenza immunization programs in low- and middle-income countries: Rationale and main conclusions of the WHO preferred product characteristics for next-generation influenza vaccines. [PDF]

, 2017
In 2017, WHO convened a working group of global experts to develop the Preferred Product Characteristics (PPC) for Next-Generation Influenza Vaccines. PPCs are intended to encourage innovation in vaccine development.
Bresee, Joseph S, de la Hoz, Fernando, Johansen, Kari, Karron, Ruth A, Krishnan, Anand, Madhi, Shabir A, Mangtani, Punam, Neuzil, Kathleen M, Ortiz, Justin R, Spiro, David J, WHO Preferred Product Characteristics for Next-Generation Influe   +10 more
core   +1 more source

MF59-adjuvanted influenza vaccine (FLUAD®) elicits higher immune responses than a non-adjuvanted influenza vaccine (Fluzone®): A randomized, multicenter, Phase III pediatric trial in Mexico

Human Vaccines & Immunotherapeutics, 2018
The poor immune response elicited by trivalent influenza vaccines (TIVs) in children can be enhanced by the addition of adjuvants. This observer-blind, randomized Phase III trial assessed the immunogenicity and safety of the MF59-adjuvanted trivalent ...
Aurelio Cruz-Valdez, Gabriel Valdez-Zapata, Sanjay S. Patel, Flavia V. Castelli, Marcia G. Garcia, Wim T. Jansen, Ashwani Kumar Arora, Esther Heijnen   +7 more
doaj   +1 more source

INDUCTION OF SECONDARY BACTERIAL PNEUMONIA IN MICE INFECTED WITH PANDEMIC AND LABORATORY STRAINS OF THE H1N1 INFLUENZA VIRUS

Журнал микробиологии, эпидемиологии и иммунобиологии, 2019
Aim. In this study we developed and characterized a mouse model of secondary S. aureus and S. pneumoniae pneumonia following influenza virus infection with H1N1 pandemic and laboratory strains and their reassortment. Materials and methods.
I. A. Leneva, A. Yu. Egorov, I. N. Falynskova, N. R. Маkhmudоvа, N. P. Kartashova, E. A. Glubokova, N. O. Vartanova, A. V. Poddubikov   +7 more
doaj   +1 more source

Heterologous prime-boost vaccination with H3N2 influenza viruses of swine favors cross-clade antibody responses and protection [PDF]

, 2017
The emergence of multiple novel lineages of H1 and H3 influenza A viruses in swine has confounded control by inactivated vaccines. Because of substantial genetic and geographic heterogeneity among circulating swine influenza viruses, one vaccine strain ...
Claes, Gerwin, Cox, Eric, Krammer, Florian, Mancera Gracia, José Carlos, Qiu, Yu, Sys, Lieve, Trus, Ivan, Van Reeth, Kristien, Versnaeyen, Han   +8 more
core   +2 more sources

Midwives\u27 knowledge, attitudes and learning needs regarding antenatal vaccination [PDF]

, 2018
Objective: To determine the knowledge, attitudes and learning needs of midwives regarding antenatal vaccination. Design & Setting: A cross-sectional, paper-based survey of midwives employed at the only public tertiary maternity hospital in the Australian
Amirthalingam, Annette K. Regan, Bonville, Borbasi, Dabrera, Danielle Engelbrecht, Donna B Mak, Dube, Eppes, Groom, Hauck, Healy, Henninger, Ishola, Janice Butt, Kissin, Lee, Lisa Nicolaou, Liu, MacDougall, Maertens, Mak, McCarthy, Paul V Effler, Regan, Rikki Priest, Robbins, Ronit Cukierman, Schneider, Tong, Vila-Candel, Yvonne Hauck, Zaman   +32 more
core   +2 more sources