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Vaccination against influenza is the most effective approach for reducing influenza morbidity and mortality. However, influenza vaccines are unique among all licensed vaccines as they are updated and administered annually to antigenically match the ...
Surender Khurana
doaj +1 more source
COVID‐19 in the Pacific territories: Isolation, borders and the complexities of governance
Abstract Early experience of COVID‐19 in seven Pacific politically dependent territories (Guam, American Samoa, Pitcairn, Tokelau, French Polynesia, Wallis and Futuna, and New Caledonia) emphasises a diversity of contexts, responses, outcomes and possible futures.
John Connell
wiley +1 more source
Projected impact of a plant-derived vaccine on the burden of seasonal influenza in Canada
Objective The analysis estimates projected population outcomes resulting from the introduction of a plant-derived influenza vaccine formulated as quadrivalent virus-like particles (QVLP) in Canada.
Lauren Ramjee+7 more
doaj +1 more source
Virus-Vectored Influenza Virus Vaccines
Despite the availability of an inactivated vaccine that has been licensed for >50 years, the influenza virus continues to cause morbidity and mortality worldwide.
Ralph A. Tripp, S. Mark Tompkins
doaj +1 more source
To the Editor: —The current comment in your issue of October 19 prompts me to call attention to the efforts of this laboratory and base hospital to do something specific for influenza. It was obvious from the first that the virus was an overwhelming one, and it was noteworthy that uncomplicated influenza was associated with leukopenia and that the ...
openaire +2 more sources
The post-2009 influenza pandemic era : time to revisit antibody immunodominance [PDF]
The current inactivated influenza vaccines rely on the induction of neutralizing antibodies against the head domain of the viral hemagglutinin (HA). The HA head contains five immunodominant antigenic sites, all of which are subject to antigenic drift ...
Caton+6 more
core +1 more source
Adjuvanted influenza vaccines [PDF]
The search for adjuvants has been stimulated by the need to ensure greater protection against influenza among subjects who show a reduced immune response to conventional influenza vaccines. Aluminum salts have long been used but are not considered satisfactory.
N. Principi+1 more
openaire +7 more sources
COVID‐19 and myasthenia gravis: A review of neurological implications of the SARS‐COV‐2
Abstract Introduction This review highlights the potential mechanisms of neuromuscular manifestation of COVID‐19, especially myasthenia gravis (MG). Methods An extensive literature search was conducted by two independent investigators using PubMed/MEDLINE and Google Scholar from its inception to December 2020. Results Exacerbations of clinical symptoms
Syed Muhammad Ismail Shah+10 more
wiley +1 more source
The influenza vaccine is not included in China’s national immunization program. Here, we assessed influenza vaccine coverage among Shanghai residents and estimated the impacts of the coronavirus disease 2019 (COVID-19) epidemic and a hypothetical free ...
Yehong Zhou+3 more
doaj +1 more source
Data and product needs for influenza immunization programs in low- and middle-income countries: Rationale and main conclusions of the WHO preferred product characteristics for next-generation influenza vaccines. [PDF]
In 2017, WHO convened a working group of global experts to develop the Preferred Product Characteristics (PPC) for Next-Generation Influenza Vaccines. PPCs are intended to encourage innovation in vaccine development.
Bresee, Joseph S+10 more
core +1 more source