Protective efficacy of a broadly cross-reactive swine influenza DNA vaccine encoding M2e, cytotoxic T lymphocyte epitope and consensus H3 hemagglutinin [PDF]
, 2012 BACKGROUND: Pigs have been implicated as mixing reservoir for the generation of new pandemic influenza strains, control of swine influenza has both veterinary and public health significance.
Bin Wang +5 more
core +1 more source
A review of the changes to the licensing of influenza vaccines in Europe [PDF]
, 2015 In 2014, the European Committee for Medicinal Products for Human Use (CHMP) published a draft regulatory guideline for the evaluation of influenza vaccines.
Voordouw, A.C.G. (Bettie) +1 more
core +2 more sources
Vaccines, 2018 Vaccination against influenza is the most effective approach for reducing influenza morbidity and mortality. However, influenza vaccines are unique among all licensed vaccines as they are updated and administered annually to antigenically match the ...
Surender Khurana
doaj +1 more source
A dose-ranging study in older adults to compare the safety and immunogenicity profiles of MF59®-adjuvanted and non-adjuvanted seasonal influenza vaccines following intradermal and intramuscular administration [PDF]
, 2014 Strategies to optimize responses to seasonal influenza vaccination in older adults include the use of adjuvants, higher antigen doses, and intradermal delivery.
Castellino, Flora +9 more
core +1 more source
Projected impact of a plant-derived vaccine on the burden of seasonal influenza in Canada
Human Vaccines & Immunotherapeutics, 2021 Objective The analysis estimates projected population outcomes resulting from the introduction of a plant-derived influenza vaccine formulated as quadrivalent virus-like particles (QVLP) in Canada.
Lauren Ramjee +7 more
doaj +1 more source
Immunogenicity and tolerability of an MF59-adjuvanted, egg-derived, A/H1N1 pandemic influenza vaccine in children 6-35 months of age [PDF]
, 2014 Background: Vaccines against pandemic A/H1N1 influenza should provide protective immunity in children, because they are at greater risk of disease than adults.
Abarca, Katia +9 more
core +2 more sources
JAMA: The Journal of the American Medical Association, 1918 To the Editor: —The current comment in your issue of October 19 prompts me to call attention to the efforts of this laboratory and base hospital to do something specific for influenza. It was obvious from the first that the virus was an overwhelming one, and it was noteworthy that uncomplicated influenza was associated with leukopenia and that the ...
openaire +2 more sources
Challenges of Making Effective Influenza Vaccines.
Annual Review of Virology, 2020 Seasonal influenza vaccines prevent influenza-related illnesses, hospitalizations, and deaths. However, these vaccines are not as effective as other viral vaccines, and there is clearly room for improvement.
S. Gouma, E. M. Anderson, S. Hensley
semanticscholar +1 more source
Cell culture-derived flu vaccine: Present and future
Human Vaccines & Immunotherapeutics, 2018 The benefit of influenza vaccines is difficult to estimate due to the complexity of accurately assessing the burden of influenza. To improve the efficacy of influenza vaccines, vaccine manufacturers have developed quadrivalent influenza vaccine (QIV ...
Alberto Pérez Rubio, Jose María Eiros
doaj +1 more source
Overview of Serological Techniques for Influenza Vaccine Evaluation: Past, Present and Future [PDF]
, 2014 Serological techniques commonly used to quantify influenza-specific antibodies include the Haemagglutination Inhibition (HI), Single Radial Haemolysis (SRH) and Virus Neutralization (VN) assays.
Callow +30 more
core +3 more sources