Results 21 to 30 of about 2,123,414 (312)

Mechanistic insights into the effect of humidity on airborne influenza virus survival, transmission and incidence

Journal of the Royal Society Interface, 2019
Influenza incidence and seasonality, along with virus survival and transmission, appear to depend at least partly on humidity, and recent studies have suggested that absolute humidity (AH) is more important than relative humidity (RH) in modulating ...
L. Marr, J. Tang, Jennifer Van Mullekom, S. Lakdawala   +3 more
semanticscholar   +1 more source

Influenza virus-related critical illness: pathophysiology and epidemiology

Critical Care, 2019
Influenza virus affects the respiratory tract by direct viral infection or by damage from the immune system response. In humans, the respiratory epithelium is the only site where the hemagglutinin (HA) molecule is effectively cleaved, generating ...
A. Kalil, P. Thomas
semanticscholar   +1 more source

Influenza Virus Neuraminidase Structure and Functions

Frontiers in Microbiology, 2019
With the constant threat of emergence of a novel influenza virus pandemic, there must be continued evaluation of the molecular mechanisms that contribute to virulence.
J. McAuley, B. Gilbertson, S. Trifkovic, L. Brown, J. McKimm-Breschkin   +4 more
semanticscholar   +1 more source

Influenza A virus is transmissible via aerosolized fomites

Nature Communications, 2020
Influenza viruses are presumed, but not conclusively known, to spread among humans by several possible routes. We provide evidence of a mode of transmission seldom considered for influenza: airborne virus transport on microscopic particles called ...
Sima Asadi, Nassima Gaaloul ben Hnia, R. Barre, A. Wexler, W. Ristenpart, Nicole M. Bouvier   +5 more
semanticscholar   +1 more source

Middle East respiratory syndrome coronavirus infection in non-camelid domestic mammals

Emerging Microbes and Infections, 2019
Dromedary camels are natural host of the Middle East respiratory syndrome coronavirus (MERS-CoV). However, there are limited studies of MERS-CoV infection of other domestic mammals exposed to infected dromedaries.
Ahmed Kandeil, Mokhtar Gomaa, Mahmoud Shehata, Ahmed El-Taweel, Ahmed E. Kayed, Awatef Abiadh, Jamel Jrijer, Yassmin Moatasim, Omnia Kutkat, Ola Bagato, Sara Mahmoud, Ahmed Mostafa, Rabeh El-Shesheny, Ranawaka APM Perera, Ronald LW Ko, Nagla Hassan, Basma Elsokary, Lotfi Allal, Ahmed Saad, Heba Sobhy, Pamela P. McKenzie, Richard J. Webby, Malik Peiris, Mohamed A. Ali, Ghazi Kayali   +24 more
doaj   +1 more source

Naturally Available Flavonoid Aglycones as Potential Antiviral Drug Candidates against SARS-CoV-2

Molecules, 2021
Flavonoids are important secondary plant metabolites that have been studied for a long time for their therapeutic potential in inflammatory diseases because of their cytokine-modulatory effects.
Ahmed A. Al-Karmalawy, Mai M. Farid, Ahmed Mostafa, Alia Y. Ragheb, Sara H. Mahmoud, Mahmoud Shehata, Noura M. Abo Shama, Mohamed GabAllah, Gomaa Mostafa-Hedeab, Mona M. Marzouk   +9 more
doaj   +1 more source

Inhibition of H1N1 influenza virus infection by zinc oxide nanoparticles: another emerging application of nanomedicine

Journal of Biomedical Sciences, 2019
Currently available anti-influenza drugs are often associated with limitations such as toxicity and the appearance of drug-resistant strains. Therefore, there is a pressing need for the development of novel, safe and more efficient antiviral agents.
H. Ghaffari, A. Tavakoli, A. Moradi, A. Tabarraei, F. Bokharaei-Salim, Masoumeh Zahmatkeshan, M. Farahmand, D. Javanmard, S. J. Kiani, Maryam Esghaei, Vahid Pirhajati-Mahabadi, A. Ataei-Pirkooh, S. Monavari   +12 more
semanticscholar   +1 more source

Diversity of Astroviruses Circulating in Humans, Bats, and Wild Birds in Egypt

Viruses, 2020
Astroviruses belong to Astroviridae family which includes two main genera: Mamastroviruses that infect mammals, and Avastroviruses that infect avian hosts. Bats and wild birds are considered among the natural reservoirs for astroviruses.
Ahmed El Taweel, Ahmed Kandeil, Ahmed Barakat, Omar Alfaroq Rabiee, Ghazi Kayali, Mohamed Ahmed Ali   +5 more
doaj   +1 more source

Broadly protective human antibodies that target the active site of influenza virus neuraminidase

Science, 2019
Alternative influenza target There is a pressing need for a broadly protective influenza vaccine that can neutralize this constantly varying, deadly virus. Stadlbauer et al.
D. Stadlbauer, Xueyong Zhu, Meagan McMahon, J. Turner, Teddy J. Wohlbold, A. Schmitz, Shirin Strohmeier, Wenli Yu, Raffael Nachbagauer, P. Mudd, I. Wilson, A. Ellebedy, F. Krammer   +12 more
semanticscholar   +1 more source

Influenza Gain-of-Function Experiments: Their Role in Vaccine Virus Recommendation and Pandemic Preparedness

mBio, 2014
In recent years, controversy has arisen regarding the risks and benefits of certain types of gain-of-function (GOF) studies involving avian influenza viruses.
S. Schultz-Cherry, R. J. Webby, R. G. Webster, A. Kelso, I. G. Barr, J. W. McCauley, R. S. Daniels, D. Wang, Y. Shu, E. Nobusawa, S. Itamura, M. Tashiro, Y. Harada, S. Watanabe, T. Odagiri, Z. Ye, G. Grohmann, R. Harvey, O. Engelhardt, D. Smith, K. Hamilton, F. Claes, G. Dauphin   +22 more
doaj   +1 more source