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For some time it has been known that influenza viruses contain a number of distinct single-stranded RNA molecules and in the last few years conclusive evidence has been obtained to indicate that both type A and type B viruses contain eight unique polynucleotide chains.
J J, Skehel, A J, Hay
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A novel broad-spectrum treatment for respiratory virus infections : influenza-based defective interfering virus provides protection against pneumovirus infection in vivo [PDF]
Respiratory viruses represent a major clinical burden. Few vaccines and antivirals are available, and the rapid appearance of resistant viruses is a cause for concern.
Edworthy, Nicole Lynn +11 more
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Analyses of HPAI H5 viruses from poultry outbreaks across a wide Eurasian region since July 2020 including the Russian Federation, Republics of Iraq and Kazakhstan, and recent detections in migratory waterfowl in the Netherlands, revealed undetected ...
Nicola S. Lewis +21 more
doaj +1 more source
Influenza virus-related critical illness: pathophysiology and epidemiology
Influenza virus affects the respiratory tract by direct viral infection or by damage from the immune system response. In humans, the respiratory epithelium is the only site where the hemagglutinin (HA) molecule is effectively cleaved, generating ...
A. Kalil, P. Thomas
semanticscholar +1 more source
Swine Influenza Virus: Current Status and Challenge
Since swine influenza virus was first isolated in 1930, it has become endemic in pigs worldwide. Although large amount of swine influenza vaccines have been used in swine industry, swine influenza still cannot be efficiently controlled and has been an ...
Wenjun Ma
semanticscholar +1 more source
Influenza D is the only type of influenza virus that mainly affects cattle with frequent spillover to other species. Since the initial description of influenza D virus (IDV) in 2011, the virus has been found to circulate among cattle and swine populations worldwide.
Runxia Liu +4 more
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Influenza virus A infection of human monocyte and macrophage subpopulations reveals increased susceptibility associated with cell differentiation [PDF]
Influenza virus infection accounts for significant morbidity and mortality world-wide. Interactions of the virus with host cells, particularly those of the macrophage lineage, are thought to contribute to various pathological changes associated with poor
Jackson David +27 more
core +1 more source
Influenza incidence and seasonality, along with virus survival and transmission, appear to depend at least partly on humidity, and recent studies have suggested that absolute humidity (AH) is more important than relative humidity (RH) in modulating ...
L. Marr +3 more
semanticscholar +1 more source
Favipiravir, an anti-influenza drug against life-threatening RNA virus infections
Favipiravir has been developed as an anti-influenza drug and licensed as an anti-influenza drug in Japan. Additionally, favipiravir is being stockpiled for 2 million people as a countermeasure for novel influenza strains.
K. Shiraki, T. Daikoku
semanticscholar +1 more source
Alterations of membrane curvature during influenza virus budding [PDF]
Influenza A virus belongs to the Orthomyxoviridae family. It is an enveloped virus that contains a segmented and negative-sense RNA genome. Influenza A viruses cause annual epidemics and occasional major pandemics, are a major cause of morbidity and ...
Martyna, Agnieszka, Rossman, Jeremy S.
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