Results 31 to 40 of about 293,331 (266)

Sinapic Acid Suppresses SARS CoV-2 Replication by Targeting Its Envelope Protein

Antibiotics, 2021
SARS CoV-2 is still considered a global health issue, and its threat keeps growing with the emergence of newly evolved strains. Despite the success in developing some vaccines as a protective measure, finding cost-effective treatments is urgent ...
Raha Orfali, Mostafa E. Rateb, Hossam M. Hassan, Mona Alonazi, Mokhtar R. Gomaa, Noura Mahrous, Mohamed GabAllah, Ahmed Kandeil, Shagufta Perveen, Usama Ramadan Abdelmohsen, Ahmed M. Sayed   +10 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Ducks induce rapid and robust antibody responses than chickens at early time after intravenous infection with H9N2 avian influenza virus

Virology Journal, 2019
Background Compared with chickens, ducks are normally resistant to avian influenza virus without clinical signs while they habor almost all subtypes of influenza A viruses.
Jianmei Yang, Hongrui Cui, Qiaoyang Teng, Wenjun Ma, Xuesong Li, Binbin Wang, Dawei Yan, Hongjun Chen, Qinfang Liu, Zejun Li   +9 more
doaj   +1 more source

Viral respiratory infections in very low birthweight infants at neonatal intensive care unit: prospective observational study

BMJ Paediatrics Open, 2020
Background and objective Very low birthweight (VLBW) infants are highly susceptible to respiratory infections. Information about prevalence of viral respiratory infections (VRIs) in neonatal intensive care unit (NICU) is scarce.
Cristina Calvo, Inmaculada Casas, Laura Sánchez García, Francisco Pozo, Adelina Pellicer   +4 more
doaj   +1 more source

Cnicin as an Anti-SARS-CoV-2: An Integrated In Silico and In Vitro Approach for the Rapid Identification of Potential COVID-19 Therapeutics

Antibiotics, 2021
Since the emergence of the SARS-CoV-2 pandemic in 2019, it has remained a significant global threat, especially with the newly evolved variants. Despite the presence of different COVID-19 vaccines, the discovery of proper antiviral therapeutics is an ...
Hani A. Alhadrami, Ahmed M. Sayed, Hossam M. Hassan, Khayrya A. Youssif, Yasser Gaber, Yassmin Moatasim, Omnia Kutkat, Ahmed Mostafa, Mohamed Ahmed Ali, Mostafa E. Rateb, Usama Ramadan Abdelmohsen, Noha M. Gamaleldin   +11 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Respiratory microbes detected in hospitalized adults with acute respiratory infections: associations between influenza A(H1N1)pdm09 virus and intensive care unit admission or fatal outcome in Vietnam (2015–2017)

BMC Infectious Diseases, 2021
Background Acute respiratory tract infection (ARI) is a leading cause of hospitalization, morbidity, and mortality worldwide. Respiratory microbes that were simultaneously detected in the respiratory tracts of hospitalized adult ARI patients were ...
Phuong Thai Truong, Shinji Saito, Ikuyo Takayama, Hiroyuki Furuya, Binh Gia Nguyen, Thanh Van Do, Phuong Thu Phan, Cuong Duy Do, Co Xuan Dao, Thach The Pham, Tuan Quoc Dang, Chau Quy Ngo, Ngan Thi Le, Vuong Minh Bui, Dung Trung Le, Van Thi Tuong Vu, Thuy Thi Phuong Pham, Takeshi Arashiro, Tsutomu Kageyama, Noriko Nakajima   +19 more
doaj   +1 more source

Evolutionary Dynamics of H5 Highly Pathogenic Avian Influenza Viruses (Clade 2.3.4.4B) Circulating in Bulgaria in 2019–2021

Viruses, 2021
The first detection of a Highly Pathogenic Avian Influenza (HPAI) H5N8 virus in Bulgaria dates back to December 2016. Since then, many outbreaks caused by HPAI H5 viruses from clade 2.3.4.4B have been reported in both domestic and wild birds in different
Bianca Zecchin, Gabriela Goujgoulova, Isabella Monne, Annalisa Salviato, Alessia Schivo, Iskra Slavcheva, Ambra Pastori, Ian H. Brown, Nicola S. Lewis, Calogero Terregino, Alice Fusaro   +10 more
doaj   +1 more source

Influenza virus infections [PDF]

Postgraduate Medical Journal, 1973
Summary Ninety-six strains of influenza A and 113 influenza B were found in the two MRC/PHLS surveys. In the general practitioner survey the majority of strains were isolated from cases diagnosed as influenza but in hospital most came from cases diagnosed as having other respiratory infections.
openaire   +2 more sources