British Medical Bulletin, 1978 For some time it has been known that influenza viruses contain a number of distinct single-stranded RNA molecules and in the last few years conclusive evidence has been obtained to indicate that both type A and type B viruses contain eight unique polynucleotide chains.
J J, Skehel, A J, Hay
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Studies of Spanish influenza and encephalitis lethargica. [PDF]
, 2003 PhDConcomitant with the Spanish influenza and extending to the 1920s encephalitis lethargica (EL), also termed von Economo's disease or sleepy sickness, occurred in epidemic proportion.
Lo, Lily Yen-Ching
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Emerging Microbes and Infections, 2021 Analyses of HPAI H5 viruses from poultry outbreaks across a wide Eurasian region since July 2020 including the Russian Federation, Republics of Iraq and Kazakhstan, and recent detections in migratory waterfowl in the Netherlands, revealed undetected ...
Nicola S. Lewis +21 more
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An unbiased genetic screen reveals the polygenic nature of the influenza virus anti-interferon response [PDF]
, 2014 Influenza A viruses counteract the cellular innate immune response at several steps, including blocking RIG I-dependent activation of interferon (IFN) transcription, IFN-dependent upregulation of IFN-stimulated genes (ISGs) and the activity of various ...
Fernández, Yolanda +23 more
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Influenza virus A infection of human monocyte and macrophage subpopulations reveals increased susceptibility associated with cell differentiation [PDF]
, 2012 Influenza virus infection accounts for significant morbidity and mortality world-wide. Interactions of the virus with host cells, particularly those of the macrophage lineage, are thought to contribute to various pathological changes associated with poor
Jackson David +27 more
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A novel broad-spectrum treatment for respiratory virus infections : influenza-based defective interfering virus provides protection against pneumovirus infection in vivo [PDF]
, 2011 Respiratory viruses represent a major clinical burden. Few vaccines and antivirals are available, and the rapid appearance of resistant viruses is a cause for concern.
Edworthy, Nicole Lynn +11 more
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The Influenza Virus Enigma [PDF]
Cell, 2009 Both seasonal and pandemic influenza continue to challenge both scientists and clinicians. Drug-resistant H1N1 influenza viruses have dominated the 2009 flu season, and the H5N1 avian influenza virus continues to kill both people and poultry in Eurasia.
Salomon, Rachelle, Webster, Robert G.
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Alterations of membrane curvature during influenza virus budding [PDF]
, 2014 Influenza A virus belongs to the Orthomyxoviridae family. It is an enveloped virus that contains a segmented and negative-sense RNA genome. Influenza A viruses cause annual epidemics and occasional major pandemics, are a major cause of morbidity and ...
Martyna, Agnieszka, Rossman, Jeremy S.
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Middle East respiratory syndrome coronavirus infection in non-camelid domestic mammals
Emerging Microbes and Infections, 2019 Dromedary camels are natural host of the Middle East respiratory syndrome coronavirus (MERS-CoV). However, there are limited studies of MERS-CoV infection of other domestic mammals exposed to infected dromedaries.
Ahmed Kandeil +24 more
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Naturally Available Flavonoid Aglycones as Potential Antiviral Drug Candidates against SARS-CoV-2
Molecules, 2021 Flavonoids are important secondary plant metabolites that have been studied for a long time for their therapeutic potential in inflammatory diseases because of their cytokine-modulatory effects.
Ahmed A. Al-Karmalawy +9 more
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