Results 41 to 50 of about 2,293,554 (361)

Influenza Virus Neuraminidase Structure and Functions

Frontiers in Microbiology, 2019
With the constant threat of emergence of a novel influenza virus pandemic, there must be continued evaluation of the molecular mechanisms that contribute to virulence.
J. McAuley, B. Gilbertson, Sanja Trifkovic, L. Brown, J. McKimm-Breschkin   +4 more
semanticscholar   +1 more source

Evolution of an Eurasian avian-like influenza virus in naïve and vaccinated pigs [PDF]

, 2012
The latest human influenza pandemic highlights the ability of influenza viruses to jump species barriers and emerge in new hosts, as well as the role of pigs in generating viruses with pandemic potential.
Pablo R Murcia, Mario Caccamo, Baillie Gregory J., Gregory J. Baillie (110994), Doug Ormond (161033), Jennifer A. Mumford (161049), Grenfell Bryan T., Lloyd Lucy, Lloyd, Lucy, Battista Patrizia, Patrizia Battista, Jennifer A Mumford, Wood, James L.N., Patrizia Battista (161011), Ramirez-Gonzalez Ricardo H., Elton, Debra, Ormond Doug, Joseph Hughes (42279), Oliver Karen, Edward C. Holmes (35215), Battista, Patrizia, Holmes Edward C., Caccamo, Mario, Edward C Holmes, Wood, James L. N., Wood, James LN, Oliver, Karen, Caccamo Mario, Ricardo H Ramirez-Gonzalez, Wood James L. N., Hughes Joseph, Ricardo H. Ramirez-Gonzalez (161026), Ramirez-Gonzalez, Ricardo H., Joseph Hughes, Lucy Lloyd (161017), Murcia, Pablo R, Bryan T Grenfell, Debra Elton (29877), Ormond, Doug, Paul Kellam, Mario Caccamo (42188), Mumford Jennifer A., Murcia, Pablo R., Baillie, Gregory J., Karen Oliver, Debra Elton, Doug Ormond, Grenfell, Bryan T., Kellam Paul, Gregory J Baillie, Paul Kellam (6413), Pablo R. Murcia (111005), Murcia Pablo R., Elton Debra, Holmes, Edward C, James L. N. Wood (111001), Holmes, Edward C., Lucy Lloyd, Mumford, Jennifer A, Hughes, Joseph, Baillie, Gregory J, Mumford, Jennifer A., Karen Oliver (161040), Kellam, Paul, Grenfell, Bryan T, Ramirez-Gonzalez, Ricardo H, Bryan T. Grenfell (44234), James L N Wood   +67 more
core   +1 more source

Differential contribution of PB1-F2 to the virulence of highly pathogenic H5N1 influenza A virus in mammalian and avian species [PDF]

, 2011
Highly pathogenic avian influenza A viruses (HPAIV) of the H5N1 subtype occasionally transmit from birds to humans and can cause severe systemic infections in both hosts.
García-Sastre, Adolfo, García-Sastre, A., Rong Hai, Hale Benjamin G., Pena, Lindomar, Hai, Rong, John Steel, Manicassamy Balaji, Daniel R. Pérez, Pérez Daniel R., Manicassamy, Balaji, Pena, L., Benjamin G. Hale, Sutton, T., Zsuzsanna T Varga, Troy Sutton, Sutton Troy, Varga Zsuzsanna T., Hale, B.G., Varga, Zsuzsanna T, Pena Lindomar, Zsuzsanna T. Varga, Hale, Benjamin G, Balaji Manicassamy, Adolfo García-Sastre, Schmolke, M., Hai Rong, Hai, R., Daniel R Pérez, Pérez, D.R., Sutton, Troy, Steel, John, Pérez, Daniel R, Steel, J., Steel John, García-Sastre Adolfo, Manicassamy, B., Mirco Schmolke, Lindomar Pena, Benjamin G Hale, Schmolke, Mirco, Varga, Z.T., Schmolke Mirco   +42 more
core   +1 more source

Middle East respiratory syndrome coronavirus infection in non-camelid domestic mammals

Emerging Microbes and Infections, 2019
Dromedary camels are natural host of the Middle East respiratory syndrome coronavirus (MERS-CoV). However, there are limited studies of MERS-CoV infection of other domestic mammals exposed to infected dromedaries.
Ahmed Kandeil, Mokhtar Gomaa, Mahmoud Shehata, Ahmed El-Taweel, Ahmed E. Kayed, Awatef Abiadh, Jamel Jrijer, Yassmin Moatasim, Omnia Kutkat, Ola Bagato, Sara Mahmoud, Ahmed Mostafa, Rabeh El-Shesheny, Ranawaka APM Perera, Ronald LW Ko, Nagla Hassan, Basma Elsokary, Lotfi Allal, Ahmed Saad, Heba Sobhy, Pamela P. McKenzie, Richard J. Webby, Malik Peiris, Mohamed A. Ali, Ghazi Kayali   +24 more
doaj   +1 more source

Naturally Available Flavonoid Aglycones as Potential Antiviral Drug Candidates against SARS-CoV-2

Molecules, 2021
Flavonoids are important secondary plant metabolites that have been studied for a long time for their therapeutic potential in inflammatory diseases because of their cytokine-modulatory effects.
Ahmed A. Al-Karmalawy, Mai M. Farid, Ahmed Mostafa, Alia Y. Ragheb, Sara H. Mahmoud, Mahmoud Shehata, Noura M. Abo Shama, Mohamed GabAllah, Gomaa Mostafa-Hedeab, Mona M. Marzouk   +9 more
doaj   +1 more source

Pseudotype-based neutralization assays for influenza: a systematic analysis [PDF]

, 2015
The use of vaccination against the influenza virus remains the most effective method of mitigating the significant morbidity and mortality caused by this virus.
Ferrara, Francesca, Keith eGrehan, Temperton, Nigel J., George William Carnell, Craig Peter Thompson, Francesca eFerrara, Nigel James Temperton, Grehan, Keith, Carnell, George W., Thompson, Craig P., Francesca Ferrara, Keith Grehan   +11 more
core   +1 more source

Inhibition of H1N1 influenza virus infection by zinc oxide nanoparticles: another emerging application of nanomedicine

Journal of Biomedical Sciences, 2019
Currently available anti-influenza drugs are often associated with limitations such as toxicity and the appearance of drug-resistant strains. Therefore, there is a pressing need for the development of novel, safe and more efficient antiviral agents.
H. Ghaffari, A. Tavakoli, A. Moradi, A. Tabarraei, F. Bokharaei-Salim, Masoumeh Zahmatkeshan, M. Farahmand, D. Javanmard, S. J. Kiani, Maryam Esghaei, Vahid Pirhajati-Mahabadi, A. Ataei-Pirkooh, S. Monavari   +12 more
semanticscholar   +1 more source

Influenza virus activation of the interferon system

, 2015
This study was supported by the Wellcome Trust (grant number 087751/A/08/Z) and the Medical Research Council (grant number G0700848).The host interferon (IFN) response represents one of the first barriers that influenza viruses must surmount in order to ...
Fodor, Ervin, Killip, Marian J., Randall, RE, Fodor, E., Killip, MJ, Randall, Richard E., Fodor, E, Killip, M.J., Randall, R.E.   +8 more
core   +1 more source

Baloxavir susceptibility of seasonal influenza viruses during the first seven seasons of clinical use in Japan, 2017/18 to 2023/24

Eurosurveillance
BACKGROUND: Baloxavir marboxil, a cap-dependent endonuclease inhibitor, was approved in Japan in February 2018 for treatment of influenza A and B infections, making Japan the first country to introduce its clinical use.AIM: We aimed to assess baloxavir ...
the Influenza Virus Surveillance Group of Japan
doaj   +1 more source

Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses

Nature Immunology, 2019
The present vaccine against influenza virus has the inevitable risk of antigenic discordance between the vaccine and the circulating strains, which diminishes vaccine efficacy.
M. Kanekiyo, M. Joyce, Rebecca A. Gillespie, J. Gallagher, Sarah F. Andrews, Hadi M. Yassine, A. Wheatley, Brian E. Fisher, D. Ambrozak, A. Creanga, K. Leung, E. Yang, Seyhan Boyoglu-Barnum, I. Georgiev, Y. Tsybovsky, Madhu Prabhakaran, H. Andersen, W. Kong, U. Baxa, Kathryn L. Zephir, J. Ledgerwood, R. Koup, P. Kwong, Audray K. Harris, A. McDermott, J. Mascola, B. Graham, H. M. Jackson   +27 more
semanticscholar   +1 more source