Results 51 to 60 of about 1,532,012 (308)
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
BMC Infectious Diseases, 2021 Background Acute respiratory tract infection (ARI) is a leading cause of hospitalization, morbidity, and mortality worldwide. Respiratory microbes that were simultaneously detected in the respiratory tracts of hospitalized adult ARI patients were ...
Phuong Thai Truong +19 more
doaj +1 more source
Viruses, 2021 The first detection of a Highly Pathogenic Avian Influenza (HPAI) H5N8 virus in Bulgaria dates back to December 2016. Since then, many outbreaks caused by HPAI H5 viruses from clade 2.3.4.4B have been reported in both domestic and wild birds in different
Bianca Zecchin +10 more
doaj +1 more source
Insights into neutralization of animal viruses gained from study of influenza virus [PDF]
, 1991 It has long been known that the binding of antibodies to viruses can result in a loss of infectivity, or neutralization, but little is understood of the mechanism or mechanisms of this process.
Outlaw, Mark C., Dimmock, N. J.
core +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
VirusesLimited surveillance and laboratory testing for non-influenza viruses remains a challenge in Uganda. The World Health Organization (WHO) designated National Influenza Center (NIC) tested samples from patients with influenza-like illness (ILI) and severe ...
Charity A. Nassuna +19 more
doaj +1 more source
Essential role of TMPRSS2 in SARS-CoV-2 infection in murine airways
Nature Communications, 2022 The SARS-CoV-2 variant of concern Omicron, has been reported to mainly use the endocytosis pathway for viral entry, bypassing the furin/TMPRSS2 pathway utilised by other variants. Here, the authors test a panel of SARS-CoV-2 variants in TMPRSS2 knock out
Naoko Iwata-Yoshikawa +15 more
doaj +1 more source
Influenza Virus and Vaccination [PDF]
Pathogens, 2020 Influenza virus infections represent a serious public health problem causing contagious respiratory disease and substantial morbidity and mortality in humans, resulting in a considerable economic burden worldwide. Notably, the number of deaths due to influenza exceeds that of any other known pathogen.
Aitor Nogales, Marta L. DeDiego
openaire +5 more sources
The human interferon-induced MxA protein inhibits early stages of influenza A virus infection by retaining the incoming viral genome in the cytoplasm [PDF]
, 2013 The induction of an interferon-induced antiviral state is a powerful cellular response against viral infection that limits viral spread. Here we show that a pre-existing antiviral state inhibits replication of influenza A viruses in human A549 cells by ...
Xiao, Han +7 more
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source