Results 81 to 90 of about 2,123,414 (312)
Influenza virus in human exhaled breath: an observational study. [PDF]
PLoS ONE, 2008 Recent studies suggest that humans exhale fine particles during tidal breathing but little is known of their composition, particularly during infection.We conducted a study of influenza infected patients to characterize influenza virus and particle ...
Patricia Fabian +7 more
doaj +1 more source
Infectious virus in exhaled breath of symptomatic seasonal influenza cases from a college community
Proceedings of the National Academy of Sciences of the United States of America, 2017 Significance Lack of human data on influenza virus aerosol shedding fuels debate over the importance of airborne transmission. We provide overwhelming evidence that humans generate infectious aerosols and quantitative data to improve mathematical models ...
J. Yan +7 more
semanticscholar +1 more source
Advanced Functional Materials, EarlyView.This study presents a microfluidic brain microvascular network‐on‐chip (BMVasChip) to investigate endothelial barrier dysfunction caused by flavivirus non‐structural protein 1 (NS1), including virus‐ and time‐dependent vascular damage, leakiness, and dysfunction.
Monika Rajput +5 more
wiley +1 more source
A humanized mouse model identifies key amino acids for low immunogenicity of H7N9 vaccines
Scientific Reports, 2017 Influenza vaccines of H7N9 subtype are consistently less immunogenic in humans than vaccines developed for other subtypes. Although prior immunoinformatic analysis identified T-cell epitopes in H7 hemagglutinin (HA) which potentially enhance regulatory T
Yamato Wada +14 more
doaj +1 more source
Novel correlates of protection against pandemic H1N1 influenza A virus infection
Nature Network Boston, 2019 Influenza viruses remain a severe threat to human health, causing up to 650,000 deaths annually1,2. Seasonal influenza virus vaccines can prevent infection, but are rendered ineffective by antigenic drift.
S. Ng +14 more
semanticscholar +1 more source
Advanced Functional Materials, EarlyView.Porous silicon nanoparticles (PSiNPs) reprogram macrophage endocytosis of manganese@albumin‐based TLR4 nanoagonists, driving TRIF‐biased TLR4 signaling, eliciting robust proinflammatory responses, and potentiating macrophage‐mediated immunotherapeutic effects against NSCLC.
Xiaomei Zhang +9 more
wiley +1 more source
Viruses, 2019 Dromedary camels are the natural reservoirs of the Middle East respiratory syndrome coronavirus (MERS-CoV). Camels are mostly bred in East African countries then exported into Africa and Middle East for consumption. To understand the distribution of MERS-
Ahmed Kandeil +36 more
doaj +1 more source
Impacts of allergic airway inflammation on lung pathology in a mouse model of influenza A virus infection. [PDF]
PLoS ONE, 2017 Influenza A virus is the respiratory pathogen responsible for influenza. Infection by the 2009 pandemic influenza A (H1N1) virus caused severe lower airway inflammation and pneumonia.
Akira Kawaguchi +8 more
doaj +1 more source
Advanced Functional Materials, EarlyView.This study demonstrates that cholesterol in messenger RNA‐lipid nanoparticles (mRNA‐LNPs) can be completely replaced with an immunopotentiating lipid, i.e., a synthetic analogue of the C‐type lectin receptor agonist monomycoloyl glycerol (MMG‐1), without compromising physicochemical properties, in vivo transfection efficiency, and immunogenicity of the
Abhijeet G. Lokras +19 more
wiley +1 more source
Influenza Research Database: An integrated bioinformatics resource for influenza virus research
Nucleic Acids Res., 2016 The Influenza Research Database (IRD) is a U.S. National Institute of Allergy and Infectious Diseases (NIAID)-sponsored Bioinformatics Resource Center dedicated to providing bioinformatics support for influenza virus research.
Yun Zhang +27 more
semanticscholar +1 more source