Results 91 to 100 of about 12,802,058 (300)
Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana +8 more
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Access to information in digital libraries : users and digital divide [PDF]
Recognising the importance of information and knowledge in all spheres of human life, the recently held World Summit on Information Society came up with a plan of action for building a global information society. The goal of the world information society
Chowdhury, G.
core
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Data security is a key feature of future communications networks. Physical layer introduces rich physical mechanisms to increase the complexity of deciphering and provides extensive protection, but faces challenges in compatibility with commercial ...
Hanwen Luo +9 more
doaj +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Real-Time Path-Recovery Method for Open-Fiber-Cross-Connect-Based Networks
Cloud computing with direct optical paths utilizing fiber cross connects is a promising way to realize low-latency high-reliability applications cost effectively.
Hiroshi Ou +4 more
doaj +1 more source
On the Stability of Random Multiple Access with Feedback Exploitation and Queue Priority
In this paper, we study the stability of two interacting queues under random multiple access in which the queues leverage the feedback information. We derive the stability region under random multiple access where one of the two queues exploits the ...
Seddik, Karim G.
core +1 more source

