Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Disparate impacts on online information access during the Covid-19 pandemic. [PDF]
Suh J, Horvitz E, White RW, Althoff T.
europepmc +1 more source
Adaptive Information Visualization for Personalized Access to Educational Digital Libraries [PDF]
Personalization is one of the emerging ways to increase the power of modern Digital Libraries. The Knowledge Sea II system presented in this paper explores social navigation support, an approach for providing personalized guidance within the open corpus ...
Brusilovsky, Peter +2 more
core
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Rural small scale farmers' smart mobile phone usage acceptance prognosticators for agricultural marketing information access. [PDF]
Nyagadza B +5 more
europepmc +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Enhance Software-Defined Network Security with IoT for Strengthen the Encryption of Information Access Control. [PDF]
Vimal V +6 more
europepmc +1 more source
Understanding How Vulnerable Populations Use Common Information and Communications Technologies (ICTs) to Access Health Care Information [PDF]
The goal of this study is to investigate patterns of internet access via computers and cellular telephones among the population being served by the Drexel University Eleventh (11th) Street Health Center (Here after, the Center) and to determine which ...
Dalrymple, Prudence W. +2 more
core
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Utility and usability evaluation of an information diary tool to measure health information access and exposure among patients with high cardiovascular risk. [PDF]
Lim HM +6 more
europepmc +1 more source

