Results 121 to 130 of about 12,802,058 (300)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Bridging the Gap: Exploring the Relationship between Information Access and Environmental Justice in Library Practices

open access: yesFolia Toruniensia
Aims: The intersection of information access and environmental justice has become increasingly vital as communities worldwide grapple with environmental challenges. This study explores the relationship between information access and environmental justice
Oluwole Durodolu, Bolaji Oladokun
doaj   +1 more source

"You are always left with doubts": information access among HPV-positive women in Greater Buenos Aires. [PDF]

open access: yesRev Salud Publica (Bogota), 2023
Szwarc L   +3 more
europepmc   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Understanding the impacts of the COVID-19 response measures on Deaf adults in Cape Town

open access: yesAfrican Journal of Disability
Background: International literature has evidenced that Deaf people have been disadvantaged during the COVID-19 pandemic; however, there is currently little research published within the South African context.
Charlotte Slome   +2 more
doaj   +1 more source

BSGatlas: a unified Bacillus subtilis genome and transcriptome annotation atlas with enhanced information access. [PDF]

open access: yesMicrob Genom, 2021
Geissler AS   +9 more
europepmc   +1 more source

Joining the information society : access issues for Europeans [PDF]

open access: yes
not availableeconomics of technology ;
Geuna,Aldo, Steinmueller ,W. Edward
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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