Results 51 to 60 of about 1,288,742 (268)

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

THЕ RЕLATIONSHIP BЕTWЕЕN CORPORATЕ GOVЕRNANCЕ AND RISK MANAGЕMЕNT [PDF]

Annals of the University of Craiova: Economic Sciences Series, 2019
Corporatе Govеrnancе is thе branch of thе еconomy that studiеs how companiеs can bеcomе morе еfficiеnt by using institutional structurеs as constitutivе acts, organizational charts and lеgislativе framеwork.
Ionuț Riza, Dincă Aurеl, Camеlia-Maria Olari Pеrju   +2 more
doaj  

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Joint Decoupling Optimization of Frequency Offsets and Array Elements for Frequency Diverse Arrays

International Journal of Antennas and Propagation
Frequency diverse array (FDA) has a distance-angle–dependent beam direction map, which has a greater application advantage than phased array. However, due to the distance-angle coupling and periodicity of its beam direction map, it makes the parameter ...
Yuming Lu, Qinlin Li, Kefei Liao, Ningbo Xie, Hanbo Chen   +4 more
doaj   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Blockchain-Based Decentralized Energy Trading Mechanism for Interconnected Photovoltaic Microgrid Clusters

Journal of Engineering
With the widespread adoption of distributed photovoltaic (PV) systems, PV microgrids are integral to the smart grid. Blockchain technology applied to interconnected PV microgrid clusters enables secure and efficient energy trading markets, optimizing PV ...
Junwei Ma, Yao Wang, Penghui Jin, Xiaowei Hao, Feng Jing, Yang Li   +5 more
doaj   +1 more source

HCGAN: hierarchical contrast generative adversarial network for unpaired sketch face synthesis [PDF]

PeerJ Computer Science
Transforming optical facial images into sketches while preserving realism and facial features poses a significant challenge. The current methods that rely on paired training data are costly and resource-intensive.
Kangning Du, Zhen Wang, Lin Cao, Yanan Guo, Shu Tian, Fan Zhang   +5 more
doaj   +2 more sources

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source