Results 91 to 100 of about 988,108 (264)

Collision-avoidance and landing responses are mediated by separate pathways in the fruit fly, Drosophila melanogaster [PDF]

open access: yes, 2002
Flies rely heavily on visual feedback for several aspects of flight control. As a fly approaches an object, the image projected across its retina expands, providing the fly with visual feedback that can be used either to trigger a collision-avoidance ...
Dickinson, Michael H., Tammero, Lance F.
core  

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Genetics Crime and Justice [PDF]

open access: yes, 2015
This review is unashamedly from the perspective of English law because busy United Kingdom criminal law solicitors and barristers mostly wish to know what the law states, which case is a precedent case and whether the author has provided up-to-date legal
Ramage, Sally
core  

Avoiding Surprises: A Model for Informing Patients [PDF]

open access: yesThe Hastings Center Report, 2002
The standard models for what doctors must tell their patients are based on the idea of informed consent: physicians must provide the information that patients need to make treatment decisions. In fact, though, they usually provide considerably more information than this model requires.
openaire   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

TDWR information on the flight deck [PDF]

open access: yes
TDWR information on the flight deck is presented in the form of view-graphs. The following subject areas are covered: air/ground wind shear information integration research; wind shear detection/warning and avoidance system; initial experiment; and ...
Hinton, Dave
core   +1 more source

Halting Progression of Stasis Dermatitis: Community Perspectives and Strategies for Prevention [PDF]

open access: yes, 2018
Complications of stasis dermatitis including venous ulcers, osteomyelitis, and cellulitis all significantly increase morbidity and mortality of disease.
Robbins, Allison B
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Avoidance maneuevers selected while viewing cockpit traffic displays [PDF]

open access: yes
Ten airline pilots rates the collision danger of air traffic presented on cockpit displays of traffic information while they monitored simulated departures from Denver. They selected avoidance maneuvers when necessary for separation.
Ellis, S. R., Lee, E., Smith, J. D.
core   +1 more source

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