Survivin and Aurora Kinase A control cell fate decisions during mitosis
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
The Extracorporeal Life Support Organization Registry Data Quality and Integrity Program. [PDF]
Zaaqoq AM +10 more
europepmc +1 more source
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
International Association of Aquatic and Marine Science Libraries and Information Centers
core +3 more sources
Review of the Quality and Reliability of Online Arabic Content on Diabetic Retinopathy: Infodemiological Study. [PDF]
Alabdrabulridha AA +7 more
europepmc +1 more source
Analyzing the Information Flow in the Research Centers within Tarbiyyat Modares University
Mohammad Hassanzadeh +1 more
openalex +2 more sources
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Experiences and needs of patients facing incurable cancer and their relatives with informal care in psychosocial supporting centres in the Netherlands: A qualitative study. [PDF]
Siemelink SD +5 more
europepmc +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
The effects of certification of head and neck cancer centers on the survival of patients with a head and neck cancer. [PDF]
Schoffer O +12 more
europepmc +1 more source

