Results 41 to 50 of about 1,465,916 (268)

Improving BERTScore for Machine Translation Evaluation Through Contrastive Learning

open access: yesIEEE Access
BERTScore is an automatic evaluation metric for machine translation. It calculates similarity scores between candidate and reference tokens through embeddings. The quality of embeddings is crucial, but embeddings of low-resource languages tend to be poor.
Gongbo Tang, Oreen Yousuf, Zeying Jin
doaj   +1 more source

ESSENTIAL-SUBSTANTIAL, STRUCTURAL AND FUNCTIONAL BASES AND THE DEVELOPMENT PARAMETERS AND FORMATION OF INFORMATION CULTURE OF A PERSON

open access: yesВестник Северо-Кавказского федерального университета, 2022
The article deals with the modern understanding of the information culture of the person in the aspects of its manifestation and formation. The leading functions of information culture as a social, psychological and pedagogical phenomenon are revealed ...
Sergey Bobryshov, Natalia Gorbatovsckaya
doaj  

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

EXPERIENCE OF USING CLOUD COMPUTING IN NETWORK PRODUCTS FOR SCHOOL EDUCATION

open access: yesÌнформаційні технології в освіті, 2011
We study data on the use of sites in the middle grades, secondary school, and their influence on the formation of information culture of students and their level of training.
L. Sokolova, V. Olevskii, J. Olevskaya
doaj  

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

ІНФОРМАЦІЙНА КУЛЬТУРА ЯК СКЛАДОВА ПРОФЕСІОНАЛІЗМУ МЕТОДИЧНОГО ПРАЦІВНИКА

open access: yesІнформаційні технології і засоби навчання, 2010
Автори розкривають питання формування інформаційної культури методичного працівника у зв’язку з поширенням на сучасному етапі використання інформаційно-комунікаційних технологій та дають характеристику ресурсів освітнього сектору ...
Olha A. Bondar   +2 more
doaj  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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