Results 101 to 110 of about 23,407,561 (253)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Design and information technology

open access: yes, 1984
6.75; Design Policy no. 6SIGLEAvailable from British Library Document Supply Centre- DSC:GPB-4524 / BLDSC - British Library Document Supply CentreGBUnited ...
Design Research Society, London (United Kingdom)   +2 more
core  

User centred information design practices and processes at the Australian Taxation Office

open access: yes, 2008
Website © 2008 Ingenta. Article copyright remains with the publisher, society or author(s) as specified within the article.This paper discusses results from a research study in the design and implementation of information documents and products in the ...
Martin, N.   +5 more
core   +1 more source

THE DIDACTIC POTENTIAL OF VISUALIZATION OF EDUCATIONAL INFORMATION

open access: yesВестник Самарского государственного технического университета. Серия: Психолого-педагогические науки, 2015
The visual needs of society increases in modern conditions, and, arguably, that increase spreads on education. The phenomenon of visualization in various fields of science, culture and education has received a lot of attention up to now.
Sergey A. Noskov
doaj  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Bayesian Bullshit

open access: yesJournal of Mechanism and Institution Design
A bullshitter neither knows nor cares about the truth, and therefore, it has been asserted, is more pernicious than a liar. We examine this assertion within the standard model of cheap talk communication where a bullshitter is modeled as an uninformed ...
Sajan Srivastava   +2 more
doaj   +1 more source

Visibility improvement and mass segmentation of mammogram images using quantile separated histogram equalisation with local contrast enhancement

open access: yesCAAI Transactions on Intelligence Technology, 2019
In this work, the authors develop a working software-based approach named ‘linearly quantile separated histogram equalisation-grey relational analysis’ for mammogram image (MI).
Bhupendra Gupta   +2 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Design Education as a Catalyst for Change

open access: yes, 2018
Designers play a role in shaping our world, both literally and figuratively. Human lives are spent interacting with designed artefacts, systems, and processes.
Mulder, Ingrid   +9 more
core   +1 more source

Isotype in Mexico: The Untold Story

open access: yesShe Ji: The Journal of Design, Economics and Innovation
This article explores the influence of the International System of Typographic Education (Isotype) in Mexico during the 1930s. It reveals how social scientist Dr.
María del Mar Navarro
doaj   +1 more source

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