Results 121 to 130 of about 974,076 (266)

Design Rework Prediction in Concurrent Design Environment: Current Trends and Future Research Directions [PDF]

open access: yes, 2009
Organised by: Cranfield UniversityThis paper aims to present state-of-the-art and formulate future research areas on design rework in concurrent design environment. Related literatures are analysed to extract the key factors which impact design rework.
Shehab, Essam   +3 more
core  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Analysing the effects of value drivers and knowledge maturity in preliminary design decision-making.

open access: yes, 2015
The paper presents the results of a three-days experiment to test the use of informationfrom a value assessment model and from a knowledge maturity scale in decisionmakingin preliminary design.
Bertoni, Alessandro   +2 more
core  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Art, Architecture, and Design Information Competencies: Graphic Design, Interior Design, Photography, Urban and Regional Planning [PDF]

open access: yes, 2019
These ARLIS/NA reports on student information competencies reevaluates and broadens the Information Competencies for Students in Design Disciplines (2006, updated 2007).
Stephanie Beene   +7 more
core   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Information Design An introduction

open access: yes
The goal of communication-oriented design of messages should always be clarity of communication. In information design the task of the sender is actually not completed until the receivers have received and understood the intended messages.Information ...
Pettersson, Rune.
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Evolution of Information Control and Centralisation Through Stages of Complex Engineering Design Projects [PDF]

open access: yes, 2014
This paper investigates how to identify potential misalignments between actual and expected information flow patterns among activities at each design stage. We develop a dynamic network model that quantifies how much information control each activity has
Eppinger, S.D.   +5 more
core  

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