Results 121 to 130 of about 23,407,561 (253)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Information Design An introduction

The goal of communication-oriented design of messages should always be clarity of communication. In information design the task of the sender is actually not completed until the receivers have received and understood the intended messages.Information ...
Pettersson, Rune.
core  

Delegation of Administrative Authority and Responsibility for Information Assurance, Security, and Awareness

, 2008
Information ...
Information Technology
core  

Toward proactive eco-design based on engineer and eco-designer's software interface modeling [PDF]

, 2011
Lien vers la version éditeur: http://www.designsociety.org/publication/30585/toward_proactive_eco-design_based_on_engineer_and_eco-designers_software_interface_modelingIntegrating environmental concerns as well as other constrains (cost, quality, etc ...
RIO, Maud, REYES, Tatiana, ROUCOULES, Lionel   +2 more
core  

Visualizzare la complessità

And, 2020
Edgar Morin defines hyper-complexity as a characteristic of «a system that reduces its conditioning by increasing its organizational capabilities, particularly its attitude to change», that corresponds to the organization: one of the ways of ...
Miriam Mariani
doaj  

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Identification of People in a Household Using Ballistocardiography Signals Through Deep Learning

Sensors
Background: Various sensor technologies have been developed to monitor the health of older adults; however, most of them require attachment to the skin.
Karin Takahashi, Yoshinobu Tanno, Hitoshi Ueno   +2 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Characterization of Day-to-Day Spectral Variability in Ballistocardiogram-Based Individual Identification Using Neural Networks

IEEE Access
Ballistocardiogram (BCG) signals are non-invasive, non-constraining and unobtrusive physiological signals that have potential applications in long-term monitoring and biometric identification in residential environments. However, the impact of day-to-day
Karin Takahashi, Hitoshi Ueno
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source