Results 61 to 70 of about 1,882,449 (270)

Epidemic Information Diffusion: A Simple Solution to Support Community-based Recommendations in P2P Overlays

, 2015
Epidemic protocols proved to be very efficient solutions for supporting dynamic and complex information diffusion in highly dis- tributed computing infrastructures, like P2P environments.
Dazzi, Patrizio, Mordacchini, Matteo, Ricci, Laura   +2 more
core   +1 more source

STAND: A Spatio-Temporal Algorithm for Network Diffusion Simulation

, 2020
Information, ideas, and diseases, or more generally, contagions, spread over space and time through individual transmissions via social networks, as well as through external sources.
Dang Lanxue, Erdos Paul, Rodriguez Manuel Gomez, Zhong Shiran   +3 more
core   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Revisiting the death of geography in the era of Big Data: the friction of distance in cyberspace and real space

International Journal of Digital Earth, 2018
Many scholars have argued that the importance of geographic proximity in human interactions has been diminished by the use of the Internet, while others disagree with this argument. Studies have noted the distance decay effect in both cyberspace and real
Su Yeon Han, Ming-Hsiang Tsou, Keith C. Clarke   +2 more
doaj   +1 more source

Multi-hop Diffusion LMS for Energy-constrained Distributed Estimation

, 2014
We propose a multi-hop diffusion strategy for a sensor network to perform distributed least mean-squares (LMS) estimation under local and network-wide energy constraints.
Hu, Wuhua, Tay, Wee Peng
core   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Interacting Spreading Processes in Multilayer Networks: A Systematic Review

IEEE Access, 2020
The world of network science is fascinating and filled with complex phenomena that we aspire to understand. One of them is the dynamics of spreading processes over complex networked structures.
Piotr Brodka, Katarzyna Musial, Jaroslaw Jankowski   +2 more
doaj   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source