Results 71 to 80 of about 556,681 (266)

Information diffusion in social sensing

Numerical Algebra, Control and Optimization, 2016
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Vikram Krishnamurthy, William Hoiles
openaire   +3 more sources

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Coupling Individual Psychological Security and Information for Modeling the Spread of Infectious Diseases

Systems
Background: Faced with the profound impact of major infectious diseases on public life and economic development, humans have long sought to understand disease transmission and intervention strategies.
Na Li, Jianlin Zhou, Haiyan Liu, Xikai Wang   +3 more
doaj   +1 more source

An information diffusion Fano inequality

CoRR, 2015
In this note, we present an information diffusion inequality derived from an elementary argument, which gives rise to a very general Fano-type inequality. The latter unifies and generalizes the distance-based Fano inequality and the continuous Fano inequality established in [Corollary 1, Propositions 1 and 2, arXiv:1311.2669v2], as well as the ...
Gábor Braun, Sebastian Pokutta
openaire   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Delay-Driven Information Diffusion in Telegram: Modeling, Empirical Analysis, and the Limits of Competition

Big Data and Cognitive Computing
Information diffusion models developed for Twitter, Reddit, and Facebook assume network contagion and competition for shared attention. Telegram operates differently. It is built around channels rather than social graphs, and users receive posts directly
Kamila Bakenova, Oleksandr Kuznetsov, Aigul Shaikhanova, Davyd Cherkaskyi, Borys Khrushkov, Valentyn Chernushevych   +5 more
doaj   +1 more source

Patents and the Diffusion of Technical Information [PDF]

SSRN Electronic Journal, 2004
Does the disclosure requirement of the patent system encourage the diffusion of inventions? This paper builds a simple model where firms choose between patents and trade secrecy to protect inventions. Diffusion is not necessarily more likely with a patent system nor is the market for technology necessarily greater.
openaire   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Hyper-S2IR: a model for characterizing higher-order interactions and dynamics in public opinion dissemination

Frontiers in Physics
Traditional public opinion diffusion models generally assume interactions between individuals as binary pair-wise effects, which struggle to capture the higher-order complexities of multi-group interactions in social networks—such as group discussions in
Chunying Zhang, Xiangyu Li, Lu Liu, Jing Ren, Jiang Ma, Liyan Zhang   +5 more
doaj   +1 more source