Results 121 to 130 of about 1,337,694 (304)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Aerial SfM–MVS Visualization of Surface Deformation along Folds during the 2024 Noto Peninsula Earthquake (Mw7.5)

open access: yesRemote Sensing
This study aimed to map and analyze the spatial pattern of the surface deformation associated with the 2024 Noto Peninsula earthquake (Mw7.5) using structure-from-motion/multi-view-stereo (SfM–MVS), an advanced photogrammetric technique. The analysis was
Kazuki Yoshida   +4 more
doaj   +1 more source

Author Correction: Recent increases in tropical cyclone intensification rates

open access: yesNature Communications, 2019
The original version of this Article contained an error in the second sentence of the first paragraph of the ‘Quantile mapping’ section of the Methods, which incorrectly read ‘We primarily focus on results produced using an additive version of QDM26 by ...
Kieran T. Bhatia   +6 more
doaj   +1 more source

GDFW This Week

open access: yes, 1991
Weekly newsletter published for employees of the Fort Worth Division of General Dynamics containing work-related information, updates about employees, and other ...
General Dynamics Corporation. Fort Worth Division.
core  

Cybersecurity dynamics in software development environment. What system traps do exist?

open access: yes, 2020
Increasing dependency on information technology and an increasing number of cyber-attacks give rise to concerns about secure software development methods.
von Kutzschenbach, Michael   +1 more
core  

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

GDFW This Week

open access: yes, 1992
Weekly newsletter published for employees of the Fort Worth Division of General Dynamics containing work-related information, updates about employees, and other ...
General Dynamics Corporation. Fort Worth Division.
core  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

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