Results 101 to 110 of about 1,337,694 (304)
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
, 2018 The Space Dynamics Laboratory developed Geospatial Reality (GR), a Government-owned, open software architecture that enhances military/DoD system capability by visually presenting warfighters with tactically relevant, geospatial situational awareness ...
Space Dynamics Laboratory
core
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Modeling the Dynamics of an Information System
, 2003 The article concentrates on the nature of a social subsystem of an information system. It analyzes the nature of information processes of collectivity within an IS and introduces a model of IS dynamics.
Jacek Unold, Unold, Jacek
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Nonlinear dynamic investigations on rolling element bearings: A review
Advances in Mechanical Engineering, 2018 Rolling element bearings are one of the most precarious components and play an important role in the effective operation of rotating machinery. Bearings are one of the foremost sources of nonlinearity in rotating machineries which significantly affect ...
Aditya Sharma +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Generalized Thermodynamics in Complex Information Dynamics: Optimization Techniques and Applications to Mammalian Connectomes [PDF]
openNatural and artificial complex systems, composed of numerous interacting components like neurons in the brain or individuals in societies, exhibit intricate structures with varying degrees of complexity.
ROSHANA, MOJTABA
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
System Dynamics based simulation and gaming: a case of transparent competing companies [PDF]
, 2000 SITMECOM 1.0 PC is a multifunctional simulator that represents three companies competing in real time in the same market. Each firm can be simulated on a different computer, which is linked to the others in one of the following ways: via a direct cable
Ruiz del Castillo, José Carlos +2 more
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