Results 101 to 110 of about 19,190,977 (299)
The benefits of system dynamics simulation for sustainability education
, 2022 Education for Sustainable Development (ESD) is vital to the success of the United Nation¿s Sustainable Development Goals, yet it has so far proved difficult to implement.
Duggan, Jim +3 more
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Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Dynamics of the transition to renewable hydrogen
, 2022 Hydrogen gained a lot of attention as an energy carrier to achieving the goal of net-zero emissions targeted by many governments and businesses around the world.
Fazeli, Reza, Stocks, Matt, Beck, Fiona
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Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
A Novel Game Information Dynamic Model based on Fluid Mechanics: Case Study using Base Ball Data in World Series 2010 [PDF]
, 2011 We propose a procedure to form information models based on equations of fluid mechanics. A novel game information dynamic model constructed using the procedure is proposed. This model is derived from a series of approximate solutions for flow past a flat
SPOERER, Kristian +2 more
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Nonlinear dynamic investigations on rolling element bearings: A review
Advances in Mechanical Engineering, 2018 Rolling element bearings are one of the most precarious components and play an important role in the effective operation of rotating machinery. Bearings are one of the foremost sources of nonlinearity in rotating machineries which significantly affect ...
Aditya Sharma +3 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
General Dynamics Corporation Report GA-471
, 1958 From foreword: The TRIGA is a novel and unusually safe training, research, and isotope-production reactor that contains solid homogeneous uranium-zirconium-hydride-moderator fuel elements and operates at power levels in the range of from 10 kw to 250 ...
General Dynamics Corporation. General Atomic Division
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