Results 131 to 140 of about 3,171,091 (298)

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Knowledge dependencies in fuzzy information systems evaluation

open access: yes, 2005
Experience and research within the field of Information Systems Evaluation (ISE), has traditionally centered on providing tools and techniques for investment justification and appraisal, based upon explicit knowledge which encodes financial and other ...
Irani, Z   +3 more
core  

Digital information evaluation skills among students in higher education

open access: yes
Despite the advancement of technology in the internet age, many college students lack the information and communication technology (ICT) literacy skills like evaluating which is necessary to navigate and using information available at present. Evaluating
Parsazadeh, Nadia;Ali, Rosmah;Saeed, Intisar Ibrahim Ridwan
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Information Visualisation Techniques, Usability and Evaluation

open access: yes, 2014
relationships a review of methods for evaluating information visualization tools, concepts, and methodologies, and recommendations for their ...
Banissi, Ebad   +3 more
core  

Construction of Indicators of Low-Temperature Stress Levels at the Jointing Stage of Winter Wheat

open access: yesAgriculture
This study aimed to investigate the impact of low-temperature (LT) stress during the jointing stage on three most representative wheat varieties in the Huang-Huai-Hai region: “Shannong 38” (a robust winter wheat variety), “Jimai 22” (a semi-winter wheat ...
Fengyin Zhang   +9 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Ten years of MIREX: reflections, challenges and opportunities [PDF]

open access: yes, 2014
The Music Information Retrieval Evaluation eXchange (MIREX) has been run annually since 2005, with the October 2014 plenary marking its tenth iteration.
Lee, Jin Ha   +11 more
core  

Evaluation Capacity Development through Cluster Evaluation

open access: yes, 2015
Background:  The term “cluster evaluation” was first coined in 1988 by W. K. Kellogg staff in an evaluation of a Foundation-funded initiative; the concept was further developed and practiced by the Kellogg Foundation evaluation consultants and other ...
Al-Zou'bi, Lamia   +3 more
core   +1 more source

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