Results 61 to 70 of about 16,796,516 (235)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
MATEC Web of Conferences, 2018 Strapdown seekers are superior to platform seekers for their simple structure, high reliability and light weight but cannot measure the line-of-sight angle rate information for the guidance of rotation missile directly. This paper aims at the engineering
Liu YongShan, Song Li, Li JingLong
doaj +1 more source
DVL-Aided SINS In-Motion Alignment Filter Based on a Novel Nonlinear Attitude Error Model
IEEE Access, 2019 A novel nonlinear attitude error model based on square root cubature information filter (SR-CIF) is proposed aiming to speed up the convergence rate of DVL-aided strapdown inertial navigation system (SINS) in-motion initial alignment for autonomous ...
Lu Zhang +3 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
APPLICATION OF RANKING BASED ATTRIBUTE SELECTION FILTERS TO PERFORM AUTOMATED EVALUATION OF DESCRIPTIVE ANSWERS THROUGH SEQUENTIAL MINIMAL OPTIMIZATION MODELS [PDF]
ICTACT Journal on Soft Computing, 2014 In this paper, we study the performance of various models for automated evaluation of descriptive answers by using rank based feature selection filters for dimensionality reduction.
C. Sunil Kumar, R.J. Rama Sree
doaj
Labelled GM-CBMEMBER filter with adaptive track initiation
The Journal of Engineering, 2019 The initial Gaussian mixture cardinality balanced multi-target multi-Bernoulli (GM-CBMeMBer) filter does not provide track information and assumes that the target birth intensity is known as a priori, but in reality the target may appear anywhere in the ...
Hemin Sun +4 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Efficient subband adaptive filtering with oversampled GDFT filter banks [PDF]
, 1997 This paper addresses the numerical efficiency of adaptive filtering implemented in subbands. Our approach first focuses on oversampled GDFT (generalized DFT) filter banks and their potential benefits over other possible subband decompositions.
Weiss, Stephan +2 more
core +3 more sources
Exact out-of-sequence processing using the information filter
, 2022 7 S.The development of modern tracking system in the recent past is towards distributed sensor scenarios. As communication links often suffer from varying delays, timely disordered data appears. An exact solution to the general Out-of-Sequence problem is
Govaers, F., Koch, W.
core +1 more source