Results 51 to 60 of about 17,150,448 (288)

Entropic Dynamics in a Theoretical Framework for Biosystems

open access: yesEntropy, 2023
Central to an understanding of the physical nature of biosystems is an apprehension of their ability to control entropy dynamics in their environment.
Richard L. Summers
doaj   +1 more source

Issues in the teaching and learning of geometry

open access: yes, 2002
This chapter analyses a range of key issues in the teaching and learning of geometry. These include the nature of geometry, why geometry is important in the curriculum at school level and beyond, what geometry can be included at the school level, the ...
Jones, Keith
core   +1 more source

Duality in Quantum Information Geometry [PDF]

open access: yesOpen Systems & Information Dynamics, 2004
Let [Formula: see text] be a separable Hilbert space. We consider the manifold [Formula: see text] consisting of density operators ρ on [Formula: see text] such that ρp is of trace class for some p ɛ (0, 1). We say [Formula: see text] is nearby ρ if there exists C > 1 such that C−1 ρ < σ < Cρ.
openaire   +2 more sources

Ways of linking geometry and algebra, the case of Geogebra

open access: yes, 2007
This paper discusses ways of enhancing the teaching of mathematics through enabling learners to gain stronger links between geometry and algebra. The vehicle for this is consideration of the affordances of GeoGebra, a form of freely-available open-source
BSRLM Geometry Working Group   +2 more
core   +2 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Qualia: The Geometry of Integrated Information

open access: yesPLoS Computational Biology, 2009
According to the integrated information theory, the quantity of consciousness is the amount of integrated information generated by a complex of elements, and the quality of experience is specified by the informational relationships it generates. This paper outlines a framework for characterizing the informational relationships generated by such systems.
David Balduzzi, Giulio Tononi
openaire   +5 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Focus point : classical and quantum information geometry [PDF]

open access: yes, 2021
The interplay between Differential Geometry, Mathematical Statistics, Probability Theory and Quantum Mechanics resulting in the so-called field of Classical and Quantum Information Geometry represents one of the most effective examples of cross ...
Mancini, S.   +11 more
core   +1 more source

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