Results 61 to 70 of about 409,949 (290)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Graph geometry interaction learning [PDF]
, 2020 While numerous approaches have been developed to embed graphs into either Euclidean or hyperbolic spaces, they do not fully utilize the information available in graphs, or lack the flexibility to model intrinsic complex graph geometry.
Zhou, C +5 more
core
Fisher Information Matrix And Hyperbolic Geometry [PDF]
, 2015 The Fisher information matrix induces a metric on parametric spaces of families of probability density functions. We analyse here the family of normal distributions showing how hyperbolic geometry arises naturally from the Fisher information metric ...
Santos S.A. +2 more
core +1 more source
Information geometry of operator scaling
Linear Algebra and its Applications, 2022 Matrix scaling is a classical problem with a wide range of applications. It is known that the Sinkhorn algorithm for matrix scaling is interpreted as alternating e-projections from the viewpoint of classical information geometry. Recently, a generalization of matrix scaling to completely positive maps called operator scaling has been found to appear in
Takeru Matsuda, Tasuku Soma
openaire +3 more sources
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Linking geometry and algebra in the school mathematics curriculum [PDF]
, 2010 This chapter focuses on the linking of geometry and algebra in the teaching and learning of mathematics - and how, through such linking, the mathematics curriculum might be strengthened.
Jones, Keith
core
AxiomsA critical processing step for AI algorithms is mapping the raw data to a landscape where the similarity of two data points is conveniently defined. Frequently, when the data points are compositions of probability functions, the similarity is reduced to ...
Giovanni Pistone, Muhammad Shoaib
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Challenges and Opportunities in Machine Learning for Geometry [PDF]
, 2023 Over the past few decades, the mathematical community has accumulated a significant amount of pure mathematical data, which has been analyzed through supervised, semi-supervised, and unsupervised machine learning techniques with remarkable results, e.g.,
Adrià Costa-Roig +5 more
core +1 more source
Nonparametric Information Geometry [PDF]
, 2013 Submitted for publication in the Proceedings od GSI2013 Aug 28-30 2013 ...
openaire +2 more sources