Results 61 to 70 of about 17,150,448 (288)

Nonparametric Information Geometry [PDF]

open access: yes, 2013
Submitted for publication in the Proceedings od GSI2013 Aug 28-30 2013 ...
openaire   +3 more sources

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

A Unified Approach to Aitchison’s, Dually Affine, and Transport Geometries of the Probability Simplex

open access: yesAxioms
A critical processing step for AI algorithms is mapping the raw data to a landscape where the similarity of two data points is conveniently defined. Frequently, when the data points are compositions of probability functions, the similarity is reduced to ...
Giovanni Pistone, Muhammad Shoaib
doaj   +1 more source

On the Fisher Metric of Conditional Probability Polytopes

open access: yesEntropy, 2014
We consider three different approaches to define natural Riemannian metrics on polytopes of stochastic matrices. First, we define a natural class of stochastic maps between these polytopes and give a metric characterization of Chentsov type in terms of ...
Guido Montúfar, Johannes Rauh, Nihat Ay
doaj   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Optimal Nonlinear Estimation in Statistical Manifolds with Application to Sensor Network Localization

open access: yesEntropy, 2017
Information geometry enables a deeper understanding of the methods of statistical inference. In this paper, the problem of nonlinear parameter estimation is considered from a geometric viewpoint using a natural gradient descent on statistical manifolds ...
Yongqiang Cheng, Xuezhi Wang, Bill Moran
doaj   +1 more source

Multisource Fusion UAV Cluster Cooperative Positioning Using Information Geometry

open access: yesRemote Sensing, 2022
Due to the functional limitations of a single UAV, UAV clusters have become an important part of smart cities, and the relative positioning between UAVs is the core difficulty in UAV cluster applications.
Chengkai Tang   +4 more
doaj   +1 more source

Information geometry of operator scaling

open access: yesLinear Algebra and its Applications, 2022
Matrix scaling is a classical problem with a wide range of applications. It is known that the Sinkhorn algorithm for matrix scaling is interpreted as alternating e-projections from the viewpoint of classical information geometry. Recently, a generalization of matrix scaling to completely positive maps called operator scaling has been found to appear in
Takeru Matsuda, Tasuku Soma
openaire   +3 more sources

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Information Geometry for Covariance Estimation in Heterogeneous Clutter with Total Bregman Divergence

open access: yesEntropy, 2018
This paper presents a covariance matrix estimation method based on information geometry in a heterogeneous clutter. In particular, the problem of covariance estimation is reformulated as the computation of geometric median for covariance matrices ...
Xiaoqiang Hua   +3 more
doaj   +1 more source

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