Results 71 to 80 of about 407,884 (290)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

On the Fisher Metric of Conditional Probability Polytopes

open access: yesEntropy, 2014
We consider three different approaches to define natural Riemannian metrics on polytopes of stochastic matrices. First, we define a natural class of stochastic maps between these polytopes and give a metric characterization of Chentsov type in terms of ...
Guido Montúfar, Johannes Rauh, Nihat Ay
doaj   +1 more source

An introduction to differential geometry in econometrics [PDF]

open access: yes, 2000
In this introductory chapter we seek to cover sufficient differential geometry in order to understand its application to Econometrics. It is not intended to be a comprehensive review of either differential geometric theory, nor of all the applications ...
Salmon, Mark H., Marriott, Paul
core  

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

Optimal Nonlinear Estimation in Statistical Manifolds with Application to Sensor Network Localization

open access: yesEntropy, 2017
Information geometry enables a deeper understanding of the methods of statistical inference. In this paper, the problem of nonlinear parameter estimation is considered from a geometric viewpoint using a natural gradient descent on statistical manifolds ...
Yongqiang Cheng, Xuezhi Wang, Bill Moran
doaj   +1 more source

Multisource Fusion UAV Cluster Cooperative Positioning Using Information Geometry

open access: yesRemote Sensing, 2022
Due to the functional limitations of a single UAV, UAV clusters have become an important part of smart cities, and the relative positioning between UAVs is the core difficulty in UAV cluster applications.
Chengkai Tang   +4 more
doaj   +1 more source

Interest rates and information geometry [PDF]

open access: yesProceedings of the Royal Society of London. Series A: Mathematical, Physical and Engineering Sciences, 2001
20 pages, 3 ...
Brody, D C, Hughston, L P
openaire   +4 more sources

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick   +19 more
wiley   +1 more source

Sentience and the Origins of Consciousness: From Cartesian Duality to Markovian Monism

open access: yesEntropy, 2020
This essay addresses Cartesian duality and how its implicit dialectic might be repaired using physics and information theory. Our agenda is to describe a key distinction in the physical sciences that may provide a foundation for the distinction between ...
Karl J. Friston   +2 more
doaj   +1 more source

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