Results 31 to 40 of about 438,838 (312)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Discover MaterialsSustainably sourced timber is increasingly recognised as a climate-responsive construction material that can substitute emissions-intensive products while storing biogenic carbon in wood building products (WBPs).
Yi Qian +6 more
doaj +1 more source
Information infrastructure of emergency medical service in the smart city solutions
Smart Cities and Regional Development Journal, 2019 This paper was developed on the base of experience realization of the state pilot project in the field of reform of the emergency medical service (EMS) in the Odessa region (Ukraine).
Valerii LOGVINOV, Svitlana MALONOGA
doaj +1 more source
AUTOMATED RECONSTRUCTION OF WALLS FROM AIRBORNE LIDAR DATA FOR COMPLETE 3D BUILDING MODELLING [PDF]
The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2012 Automated 3D building model generation continues to attract research interests in photogrammetry and computer vision. Airborne Light Detection and Ranging (LIDAR) data with increasing point density and accuracy has been recognized as a valuable source ...
Y. He +3 more
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
ISPRS International Journal of Geo-Information, 2018 As an invaluable source of knowledge about the past, cultural heritage may be an important element of the humanities research infrastructure, along with other elements, such as spatial references.
Albina Mościcka +1 more
doaj +1 more source
Evolution of Scientific Information Services in the Context of Open Digital Science
Informaciâ i Innovacii, 2023 The article is devoted to the information infrastructure of scientific research in the European Union, which is the world leader in this field of organization of science.
A. B. Antopolsky
doaj +1 more source
Archival infrastructure and the information backlog [PDF]
Archival Science, 2021 Embedded in the notion of the archive as knowledge infrastructure is the idea of a steady flow of information that resides within and moves through socio-technical systems. While there is exponential growth in the information transferred between the creator and the archive, the information flow between the archive and the user is often leaky ...
openaire +2 more sources