Results 51 to 60 of about 433,766 (266)

Cataloguing, Indexing and Encoding

Revue d'anthropologie des connaissances, 2013
The article looks at the production and manipulation of accumulation management systems. It enters into the infrastructures designed to put in order and make accessible the accumulation of knowledge through their materiality and questions the productions,
Tiziana Nicoletta Beltrame, Christine Jungen   +1 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

„WEITER WISSEN. Mit uns.“ Ein Bericht über die Kampagne der wissenschaftlichen Bibliotheken

GMS Medizin – Bibliothek – Information
Academic libraries play a central role as a driving force for open science and society. They provide researchers, academics and students with access to information and promote media literacy.
Ostrzinski, Ulrike
doaj   +1 more source

Catalogar, indexar, codificar

Revue d'anthropologie des connaissances, 2013
The article looks at the production and manipulation of accumulation management systems. It enters into the infrastructures designed to put in order and make accessible the accumulation of knowledge through their materiality and questions the productions,
Tiziana Nicoletta Beltrame, Christine Jungen   +1 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

INFORMATION INFRASTRUCTURE OF THE EDUCATIONAL ENVIRONMENT WITH VIRTUAL MACHINE TECHNOLOGY [PDF]

Научно-технический вестник информационных технологий, механики и оптики, 2014
Subject of research. Information infrastructure for the training environment with application of technology of virtual computers for small pedagogical systems (separate classes, author's courses) is created and investigated. Research technique.
Artem D. Beresnev , Natalia F. Gusarova , Roman V. Ivanov , Dmitry N. Fedotov   +3 more
doaj  

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Addressing information poverty in enhancing Small and Medium-scale Enterprisesfor economic growth in the Global South

Folia Toruniensia
Background: The need for economic growth among the nations of the Global South has necessitated inquiries into Small and Medium-scale Enterprises (SMEs) as drivers of such growth. However, how well SMEs will function is determined by certain factors like
Magnus Igbinovia, Omorodion Okuonghae, Juliana Akidi, Smart Eromosele Ambrose   +3 more
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source