Results 61 to 70 of about 433,766 (266)

Digital Transformation and Sustainable Land Systems: The Non-Linear Impact of Information Infrastructure on Air Quality and Carbon Mitigation

Land
As the digital economy advances, information infrastructure has become a core engine for driving green economic transition and optimizing sustainable land systems. However, its heterogeneous governance effects on different types of pollutants and spatial
Hongyan Duan, Weidong Li
doaj   +1 more source

An Infrastructure for Reactive Information Environments [PDF]

, 2005
We introduce the concept of reactive information environments and a general infrastructure for experimentation with such systems. Its asynchronous state-based processing model is described along with the architectural requirements and main components of our infrastructure.
Rudi Belotti, Corsin Decurtins, Michael Grossniklaus, Moira C. Norrie   +3 more
openaire   +2 more sources

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

The Feasibility of Telemedicine Technology Implementation in the Selected Hospitals of Iran

پیاورد سلامت, 2018
Background and Aim: Successful implementation and optimum use of telemedicine technology depends on providing the necessary infrastructure and the success factors of this technology, such as high-speed broadband. The present study is aimed at feasibility
Samin Nobakht, Somayeh Bagheri, Esmaeil Mehraeen, Ahmad Reza Shamsabadi   +3 more
doaj  

Moving enterprise resource planning (ERP) systems to the cloud: the challenge of infrastructural embeddedness

International Journal of Information Systems and Project Management, 2021
Cloud enterprise resource planning (ERP) solutions allow organizations to support and coordinate key business processes by leveraging virtualization. Nevertheless, moving ERPs to the cloud is not straightforward, and organizational cloud ERP initiatives
Eli Hustad, Vegard Uri Sørheller, Emeli Høvik Jørgensen, Polyxeni Vassilakopoulou   +3 more
doaj  

Trends in information infrastructure of enterprises

Agricultural Economics (AGRICECON), 2006
This paper will focus on the development trends of enterprise information infrastructure which will take into account an effective management of institution as well as integration of the existing technologies and systems.
I. Vrana
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source