Landscape of BRAF transcript variants in human cancer
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda+5 more
wiley +1 more source
This is Why We Can’t Have Nice Things: Reclaim Your Inbox
In Brief: In this article, co-authors Lindsay Sarin and Erin Dorney experiment with managing email (testing three existing systems), explore the idea of managing communication expectations, and consider the implications these strategies could have on our
Erin Dorney
doaj
An Approach of BIM-Based Dynamic Adaptive Zoning for Group Piles Construction Multi-Work Areas
In large-scale pile foundation drilling projects, the absence of digital work area management hampers dynamic construction management, affecting efficiency.
Wei Zhou+6 more
doaj +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte+10 more
wiley +1 more source
Department of publications pitman's municipal office organisation and management: A comprehensive manual of information and direction on matters connected with the work of officials of municipalities. Edited by William Bateson, A.C.A., F.S.A.A., borough treasurer for the county borough of blackpool. With contributions by experienced authorities on municipal work and practice. With about 250 diagrams and forms. London: Sir Isaac Pitman and Sons, 1, Amen Comer, E. C. 25s. net [PDF]
Clinton Rogers Woodruff
openalex +1 more source
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton+17 more
wiley +1 more source
Automated Data Management Information System (ADMIS) [PDF]
ADMIS stores and controls data and documents associated with manned space flight effort. System contains all data oriented toward a specific document; it is primary source of reports generated by the system.
Blackstone, C.+9 more
core +1 more source
Business Process Modeling Using a Metamodeling Approach [PDF]
The thesis discusses topics related to the development of business process management systems. Business process management systems have evolved on the basis of workflow management systems through incremental inclusion of standard information system functions, for example, resource and client management.
arxiv
The relentless progression of advanced technologies has driven the seamless integration of Internet of Things (IoT) services into the fundamental framework of contemporary tourism enterprises. In the quest for valuable insights from the vast reservoir of
Lianchao Meng
doaj +1 more source
Yogesh K. Dwivedi+13 more
semanticscholar +1 more source