Results 71 to 80 of about 3,535,553 (315)

Information Systems Implementation Failure: Insights from Prism

, 2008
10.1016/j.ijinfomgt.2007.07.001International Journal of Information Management284259 ...
PAN, Shan Ling, Pan, G., Hackney, Ray, PAN, Gary Shan Chi, Hackney, R., Pan, S.L.   +5 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Construction of a chain information management system for pressure injuries based on evidence-based medicine and the Delphi method (基于循证医学与德尔菲法的压力性损伤链式信息化管理系统构建研究)

中西医结合护理
Objective In order to address the issues of delayed assessment and fragmented interventions in routine management of pressure injury (PI), this study aims to constructs chain-based information management system grounded in evidence-based practices and ...
HE Xuxu (何绪绪), ZHAO Jieqiong (赵洁琼)   +1 more
doaj   +1 more source

Technology and Information Management Supporting Resilience in Healthcare and Rescue Systems

, 2023
Health care and rescue system resilience is the multifactoral sum of technology, humans, information, processes, and management. The coronavirus (COVID-19) pandemic has been a catalyst for transformation globally and tested the resilience of health care ...
Vainikainen, Jasmin, Hannele Väyrynen, Helander, Nina, Nina Helander, Annamaija Paunu, Väyrynen, Hannele, Tenhovuori, Sini, Jasmin Vainikainen, Sini Tenhovuori, Paunu, Annamaija   +9 more
core   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Reporting on the Development of a Web-Based Prototype Dashboard for Construction Design Managers, Achieved through Design Science Research Methodology (DSRM)

Buildings
Construction Design Management (DM) involves the coordination of design processes and activities to ensure quality project design, yet it involves many challenges.
Barry Gledson, Kay Rogage, Anna Thompson, Hazel Ponton   +3 more
doaj   +1 more source

Handling network management information complexity through soft computing

, 2004
The increasing complexity of modern networks requires radical changes in network management approaches. One of the prerequisites for successful management of these complex systems is the ability to handle large amounts of information. The information may
Shahrestani, Seyed A.
core  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Human resource capacity for information management in selected public healthcare facilities in Meru County, Kenya

The Pan African Medical Journal, 2015
INTRODUCTION: reliable health information is essential for decision making in the healthcare system. Information management in Kenya was considered the weakest area under the Health Information System pillar mainly due to inadequate health workers ...
Elizabeth Mueke Kiilu, Dominic Charles Okero, Lillian Muiruri, Pacific Akinyi Owuondo   +3 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source